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梁陆军
( 特任副研究员 )
的个人主页 http://faculty.ustc.edu.cn/lianglujun/zh_CN/index.htm
特任副研究员
教师拼音名称:
lianglujun
电子邮箱:
6374b98e1a00a34f1c5d88306ccfe5bea407abbfc296c19fab0fcc93a5f84ebeab45f277eb378da8be65c9f6bee615e5e216649ed1a36971d25d790547a8691a503137322c279540eecbd49729bc7773045db13b2db68cda8b3c4a8bdf40d121909a655ff9c416f60e1197cbb566b2af3cc5e6a3e6ed79876187769a3ebe434e
联系方式:
lujun@ustc.edu.cn
学位:
博士
论文成果
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论文成果
[1]
Liang, L.-J.#, Wang, Y.#, Hua, X.#, et al. Cell-Permeable Stimuli-Responsive Ubiquitin Probe for Time-Resolved Monitoring of Substrate Ubiquitination in Live Cells. JACS Au 2023, DOI: 10.1021/jacsau.3c00421.
[2]
Liang, L.-J. #, Chu, G.-C. #, Qu, Q. #, Zuo, C., Mao, J.-X, Zheng, Q.-Y, Chen, J.-N, Meng, X.-B, Jing, Y.-W, Deng, H.-T, Li, Y.-M., Liu, L. Chemical Synthesis of Activity-Based E2-Ubiquitin Probes for the Structural Analysis of E3 Ligase-Catalyzed Transthiolation. Angew. Chem. Int. Ed. 60, 2021, 17171-17177..
[3]
Pan, M.#, Zheng, Q. -Y. #, Wang, T. #, Liang, L. -J #, Mao, J.-X, Zuo, C., Ding, R.-C, Ai, H.-S, Xie, Y., Si, D., Yu, Y.-Y, Liu, L., Zhao, M-L. Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature. 600, 2021, 334-338..
[4]
Liang, L.-J., Si, Y.-Y, Tang, S., Huang, D.-L, Wang, Z.A., Tian, C.-L, Zheng, J.-S. Biochemical properties of K11,48-branched ubiquitin chains. Chin. Chem. Lett. 29, 2018, 1155-1159.
[5]
Zhang, Z.-Q., Yang, C.-T., Liang, L.-J., Xiao, B., Lu, X., Liu, J.-H., Sun, Y.-Y., Marder, T.B., Fu, Y. Copper-catalyzed/promoted cross-coupling of gem -diborylalkanes with nonactivated primary Alkyl halides: An alternative route to alkylboronic esters. Org. Lett. 16, 2014, 6342-6345.
[6]
Tan, X.-L., Pan, M., Zheng, Y., Gao, S., Liang, L.-J., Li, Y.-M. Sortase-mediated chemical protein synthesis reveals the bidentate binding of bisphosphorylated p62 with K63 diubiquitin. Chem. Sci. 8, 2017, 6881-6887.
[7]
Si, Y.-Y., Liang, L.-J., Tang, S., Qi, Y.-K., Huang, Y.-C, Zheng, J.-S. One-pot ligation strategy for atypical ubiquitin chains synthesis by using the trifluoroacetamidomethyl-protected isopeptide-linked Ub (Tfacm-isoUb) unit. Tetrahedron Lett. 59, 2018, 268-271.
[8]
Si, Y.-Y., Liang, L.-J., Tang, S., Qi, Y.-K, Huang, Y.-C, Liu, L. Semi-synthesis of disulfide-linked branched tri-ubiquitin mimics. Sci. China Chem. 61, 2018, 412-417.
[9]
Tang, S. #, Liang, L.-J. #, Si, Y.-Y. #, Gao, S., Wang, J.-X., Liang, J., Mei, Z., Zheng, J.-S., Liu, L. Practical Chemical Synthesis of Atypical Ubiquitin Chains by Using an Isopeptide-Linked Ub Isomer. Angew. Chem. Int. Ed. 56, 2017, 13333-13337.
[10]
Pan, M. #, Zheng, Q.-Y #, Ding, S. #, Zhang, L., Qu, Q., Wang, T., Hong, D., Ren, Y.-X, Liang, L.-J, Chen, C.-L, Mei, Z., Liu, L. Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains. Angew. Chem. Int. Ed. 58, 2019, 2627-2631.
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