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DNA纳米器件与细胞分析
以G-四链体或i-motif诱导DNA框架二聚组装,利用邻近效应调控劈开的适配体与配体亲和作用,构建细胞环境响应型DNA分子纳米器件,探测细胞内源物表达水平,并进一步研究癌细胞早期凋亡及药物疗效。