谢文兵
博士生导师
硕士生导师
教师姓名：谢文兵
教师拼音名称：Xie Wenbing
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学历：博士研究生毕业
办公地点：中国科学技术大学西校区生命科学楼附楼706办公室
学位：博士
职称：特任教授
毕业院校：北京大学
所属院系：生命科学与医学部
学科：生物学
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论文成果
- Wenbing Xie, Ioannis Kagiampakis, Lixia Pan, Yang W. Zhang, Lauren Murphy, Xiangqian Kong, Limin Xia, Fillipe LF Carvlho, Subhojit Sen, Ray-Whay Chiu Yen, Cynthia A. Zahnow, Nita Ahuja, Stephen B. Baylin* and Hariharan Easwaran*. (2018) "DNA methylation patterns separate senescence from transformation potential and indicate cancer risk". Cancer Cell. 33(2):309-321.e5.
- Yang W. Zhang, Zhihong Wang, Wenbing Xie, Yi Cai, Limin Xia, Hariharan Easwaran, Jianjun Luo, Ray-Whay Chiu Yen, Yana Li, Stephen B. Baylin. (2017) "Acetylation enhances TET2 function in protecting against abnormal DNA methylation during oxidative stress". Molecular Cell. 65(2):323-335.
- Wenbing Xie#, Te Ling#, Yonggang Zhou#, Weijun Feng, Qiaoyun Zhu, Henk Stunnenberg, Ingrid Grummt and Wei Tao. (2012) "The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions". Proc Natl Acad Sci U.S.A. 109(21): 8161-8166. (#Co-first author).
- Limin Xia#, Wenjie Huang#, Marina Bellani, Michael M. Seidman, Kaichun Wu, Daiming Fan, Yongzhan Nie, Yi Cai, Yang W. Zhang, Lirong Yu, Huili Li, Cynthia A. Zahnow, Wenbing Xie, Ray-Whay Chiu Yen, Feyruz V. Rassool, Stephen B. Baylin. (2017) "CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes". Cancer Cell. 31: 653–668. DOI: 10....
- Shijiao Huang, Xiaowei Xu, Guopeng Wang, Guoliang Lu, Wenbing Xie, Wei Tao, Hongyin Zhang, Qing Jiang and Chuanmao Zhang. (2016) "DNA Replication Initiator Cdc6 also Regulates Ribosomal DNA Transcription Initiation". J Cell Sci. 129: 1429-1440.
- Min Luo#, Te Ling#, Wenbing Xie#, He Sun#, Yonggang Zhou, Qiaoyun Zhu, Meili Shen, Le Zong, Guoliang Lyu, Yun Zhao, Tao Ye, Jun Gu, Wei Tao, Zhigang Lu and Ingrid Grummt. (2013) "NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells". Stem Cells. 31(7): 1278-1286. (#Co-first author).
- Zhihao Lu#, Jianling Zou#, Shuang Li#, Michael J. Topper, Yong Tao, Hao Zhang, Xi Jiao, Wenbing Xie, Xiangqian Kong, Michelle Vaz, Huili Li, Yi Cai, Limin Xia, ......, Cynthia A. Zahnow, Drew M. Pardoll, Franck Housseau, Stephen B. Baylin*, Lin Shen*, Malcolm V. Brock*. (2020) "Epigenetic therapy inhibits metastases by disrupting premetastatic niches". Nature. 579(7798):284-290.
- Guoliang Lyu#, Le Zong#, Chao Zhang, Xiaoke Huang, Wenbing Xie, Junnan Fang, Yiting Guan, Lijun Zhang, Ting Ni, Jun Gu, Wei Tao. (2018) "Metastasis-related methyltransferase Merm1 represses the methyltransferase activity of Dnmt3a and facilitates RNA polymerase I transcriptional elongation". Journal of Molecular Cell Biology. doi.org/10.1093/jmcb/mjy023.
- Xiangqian Kong#, Jie Chen#, Wenbing Xie#, Stephen M. Brown, Yi Cai, Kaichun Wu, Daiming Fan, Yongzhan Nie, Rochelle L. Tiedemann, Yong Tao, Ray-Whay Chiu Yen, Michael J. Topper, Cynthia A. Zahnow, Hariharan Easwaran, Scott B. Rothbart*, Limin Xia*, Stephen B. Baylin*. (2019) "Defining UHRF1 Domains That Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties". Cancer ...
- Te Ling#, Wenbing Xie#, Min Luo#, Meili Shen, Qiaoyun Zhu, Le Zong, Tingting Zhou, Jun Gu, Zhigang Lu, Feixiong Zhang and Wei Tao. (2013) "CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5". Biochem Biophys Res Commun. 437(1): 101-107. (#Co-first author).
- Yong Tao#, Byunghak Kang#, Daniel Petkovich, Julie In, Genevieve Stein-O'Brien, Xiangqian Kong, Wenbing Xie, Nicholas Zachos, Shinji Maegawa, Stephen Brown, Ray-Whay Chiu Yen, Jai Thakor, Zhihao Lu, Yuezheng Zhang, ...... Cynthia A. Zahnow, Nita Ahuja, Elana Fertig, Jean-Pierre Issa, Stephen B. Baylin*, Hariharan Easwaran*. (2019) "Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Act...
- Fei Ye#, Xiangqian Kong#, Shijie Chen, Hao Zhang, Yan Liu, Zhiyuan Shao, Jia Jin, Yi Cai, Rukang Zhang, Linjuan Li, Yang W. Zhang, Yu-Chih Liu, Chenhua Zhang, Wenbing Xie, Kunqian Yu, Hong Ding, Kehao Zhao, Hualiang Jiang, Stephen B. Baylin* and Cheng Luo*. (2018) "Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase...
- Lixia Pan, Wenbing Xie, Kai-Le Li, Zhihao Yang, Jiang Xu, Wenhao Zhang, Lu-Ping Liu, Xingjie Ren, Zhimin He, Junyu Wu, Jin Sun, Hui-Min Wei, Da-Liang Wang, Wei Xie, Wei Li, Jian-Quan Ni*, and Fang-Lin Sun*. (2015) "Heterochromatin remodeling by CDK12 contributes to learning in Drosophila". Proc Natl Acad Sci U.S.A. 112(45): 13988-13993.
- Wenbing Xie, Stephen B. Baylin, Hariharan Easwaran. (2019) "DNA methylation in senescence, aging and cancer". Oncoscience. 6 (1): 291-293.
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