(II) Small Angle X-ray Scattering (SAXS) is powerful tool in elucidating the structures of multi-domain proteins or large protein complexes when combing with other structural biology techniques. SAXS can provide the low-resolution envelope of large bio-macromolecule to accommodate the high-resolution structures of subunits solved by NMR or X-ray crystallography, and direct the generation of the high-resolution structure of bio-macromolecule with the help of Molecular Dynamics MD) simulation. The specific methods are still in developing.

• (II) Small Angle X-ray Scattering (SAXS) is powerful tool in elucidating the structures of multi-domain proteins or large protein complexes when combing with other structural biology techniques. SAXS can provide the low-resolution envelope of large bio-macromolecule to accommodate the high-resolution structures of subunits solved by NMR or X-ray crystallography, and direct the generation of the high-resolution structure of bio-macromolecule with the help of Molecular Dynamics MD) simulation. The specific methods are still in developing.