Focus scanning with feedback-control for fiber-optic nonlinear endomicroscopy
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DOI码：10.1364/BOE.8.002519
发表刊物：Biomedical Optics Express
摘要：Fiber-optic endomicroscopes open new avenues for the application of non-linear optics to novel in vivo applications. To achieve focus scanning in vivo, shape memory alloy (SMA) wires have been used to move optical elements in miniature endomicroscopes. However, this method has various limitations, making it difficult to achieve accurate and reliable depth scanning. Here we present a feedback-controlled SMA depth scanner. With a Hall effect sensor, contraction of the SMA wire can be tracked in real time, rendering accurate and robust control of motion. The SMA depth scanner can achieve up to 490 µm travel and with open-loop operation, it can move more than 350 µm within one second. With the feedback loop engaged, submicron positioning accuracy was achieved along with superior positioning stability. The high-precision positioning capability of the SMA depth scanner was verified by depth-resolved nonlinear endomicroscopic imaging of mouse brain samples.
合写作者：Wenxuan Liang,Honghua Guan,Yung-Tian A. Gau,Dwight E. Bergles
第一作者：Ang Li
通讯作者：Xingde Li
文献类型：J
卷号：8
期号：5
页面范围：2519-2527
是否译文：否
发表时间：2017-04-17
收录刊物：SCI
发布期刊链接：https://opg.optica.org/boe/fulltext.cfm?uri=boe-8-5-2519&id=363054