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同专业博导
同专业硕导
郑基深
的个人主页 http://faculty.ustc.edu.cn/zheng_lab/zh_CN/index.htm
博士生导师 硕士生导师
教师拼音名称:
zheng
电子邮箱:
8c8f36b87a976462da230fc9fcaf507b1760c19ce29e877198cffb8e26c9eef2b1e6714d34f5dab1971c9951464e56f534dad7f7b20038c5ccff304d13edcaaaa0fd512c0a36def8fc2179ae7314f982cce8798da438fb93808f6c7325ad707f0692706d13eb8c0fa7ce2c90d9348e0704f8a5b672639d6130265e4bf49a2e2f
职务:
教授
办公地点:
中国科大西区生命科学楼附楼K905
联系方式:
0551-63607782
学位:
博士
毕业院校:
中国科学技术大学
学科:
生物学
化学
生物医学工程
论文成果
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中科大郑基深课题组
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论文成果
[11]
Li, Y.; Heng, J.; Sun, D.; Zhang, B.; Zhang, X.; Zheng, Y.; Shi, W. W.; Wang, T. Y.; Li, J. Y.; Sun, X.; Liu, X.; Zheng, J. S.*; Kobilka, B. K.; Liu, L.*,Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor beta2-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus.J. Am. Chem. Soc.,2021,143,17566-17576.
[12]
Montigny, C.; Huang, D. L.; Beswick, V.; Barbot, T.; Jaxel, C.; le Maire, M.; Zheng, J. S.*; Jamin, N.,Sarcolipin alters SERCA1a interdomain communication by impairing binding of both calcium and ATP.Sci. Rep.,2021,11,1641.
[13]
Li, Y.; Cao, X.; Tian, C.; Zheng, J. S.*,Chemical protein synthesis-assisted high-throughput screening strategies for d-peptides in drug discovery.Chin. Chem. Lett.,2020,31,2365-2374.
[14]
Huang, D.-L.; Li, Y.; Liang, J.; Yu, L.; Xue, M.; Cao, X.-X.; Xiao, B.; Tian, C.-L.; Liu, L.; Zheng, J. S.*,The New Salcylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis.J. Am. Chem. Soc.,2020,142,8790-8799.
[15]
Qu, Q.; Gao, S.; Wu, F. M.; Zhang, M. G.; Li, Y; Zhang, L. H., Donald Bierer, Tian, C. L.*, Zheng, J. S.*; Liu, L.*,Synthesis of disulfide surrogate peptides incorporating large-span surrogate bridges through a native chemical ligation-assisted diaminodiacid strategy.Angew. Chem. Int. Ed.,2020,59,6037-6045.
[16]
Huang, D. L.; Montigny, C.; Zheng, Y.; Beswick, V.; Li, Y.; Cao, X. X.; Barbot, T.; Jaxel, C.; Liang, J.; Tian, C. L.; Jamin, N.; Zheng, J. S.*,Chemical Synthesis of Native S-palmitoylated Membrane Proteins through Reversible Backbone Modification Assisted Ser/Thr Ligation.Angew. Chem. Int. Ed.,2020,59,5178-5184.
[17]
Zhang, B.; Deng, Q.; Zuo, C.; Yan, B.; Zuo, C.; Cao, X. X.; Zhu, T. F.; Zheng, J. S.*; Liu, L.*,Ligation of Soluble but Unreactive Peptide Segments in the Chemical Synthesis of Haemophilus Influenzae DNA Ligase.Angew. Chem. Int. Ed.,2019,58,12231-12237.
[18]
Zuo C.; Zhang B.; Yan B.; Zheng, J. S.*,One-pot multi-segment condensation strategies for chemical protein synthesis.Org. Biomol. Chem.,2019,17,727-744.
[19]
Guo, Q. Y.; Zhang, L. H.; Zuo, C.; Huang, D. L.; Wang, Z. A.; Zheng, J. S.*; Tian, C. L.*,Channel activity of mirror-image M2 proton channel of influenza A virus is blocked by achiral or chiral inhibitors.Protein Cell,2019,10,211-216.
[20]
Qi, Y.-K.*; Si, Y.-Y.; Du, S.-S.; Liang, J.; Wang, K.-W.*; Zheng, J. S.*,Recent advances in the chemical synthesis and semi-synthesis of poly-ubiquitin-based proteins and probes.Sci. China Chem.,2019,62,299-312.
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