臧建业
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臧建业
研究领域
课题组主要应用结构生物学、生物化学、分子生物学、化学生物学等方法解析着丝粒-动粒组装调控机制、组蛋白翻译后修饰的调控与识别机制等科学问题，揭示染色质高级结构动态调控的重要生理、病理意义，为肿瘤等相关疾病的药物研发提供理论依据。
论文成果
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Zhan L#, Liu C#, Qi K, Wu L, Xiong Y, Zhang X*, Zang J* & Pan Y*. Enhanced imaging of endogenous metabolites by negative ammonia assisted DESI/PI mass spectrometry. Talanta. 2023; 252: 123864.,
Tian T#, Chen L#, Dou Z#, Yang Z#, Gao X*, Yuan X, Wang C, Liu R, Shen Z, Gui P, Teng M, Meng X, Hill DL, Li L, Zhang X, Liu X, Sun L*, Zang J* & Yao X*. Structural insights into human CCAN complex assembled onto DNA. Cell Discov. 2022; 8: 90.,
Zu H#, Li C#, Dai C#, Pan Y, Ding C, Sun H, Zhang X, Yao X*, Zang J* & Mo X*. SIRT2 functions as a histone delactylase and inhibits the proliferation and migration of neuroblastoma cells. Cell Discov. 2022; 8: 54.,
Jia N#, Li G, Wang X, Cao Q, Chen W, Wang C, Chen L, Ma X, Zhang X, Tao Y*, Zang J*, Mo X* & Hu J*. Staphylococcal superantigen-like protein 10 induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathways. Commun Biol. 2022; 5: 813.,
Zhao J#, Chen W#, Pan Y#, Zhang Y, Sun H, Wang H, Yang F, Liu Y, Shen N*, Zhang X*, Mo X* & Zang J*. Structural insights into the recognition of histone H3Q5 serotonylation by WDR5. Sci Adv. 2021; 7.,
Zhang M#, Zheng F#, Xiong Y, Shao C, Wang C, Wu M, Niu X, Dong F, Zhang X*, Fu C* & Zang J*. Centromere targeting of Mis18 requires the interaction with DNA and H2A-H2B in fission yeast. Cell Mol Life Sci. 2021; 78: 373-384.,
著作成果
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