Qr code
Login 中文
HU JINMING

Professor

Supervisor of Doctorate Candidates

Supervisor of Master's Candidates


E-Mail:

Business Address:中国科学技术大学东区环境资源楼

Alma Mater:中国科学技术大学

Discipline:Chemistry

Academic Honor

2017   National outstanding youth fund winner

2024   Winner of National Science Fund for Distinguished Young Scholars

MOBILE Version
Click:Times

The Last Update Time: ..

Profile

胡进明，中国科学技术大学高分子科学与工程系教授，博士生导师；中国科学技术大学附属第一医院（安徽省立医院）特聘专家。2007年本科毕业于合肥工业大学，2012年博士毕业于中国科学技术大学，导师刘世勇教授。2013-2015年分别在澳大利亚新南威尔士大学和莫纳什大学从事博士后研究，合作导师均为Thomas P Davis教授。2016年入职中国科学技术大学高分子科学与工程系，先后担任特任研究员、特任教授、教授。 

主要从事高分子材料可控合成、自组装调控及其生物医学功能应用研究，近期研究集中在气体药物（一氧化氮、一氧化碳

和硫化氢）递送高分子材料的可控合成及其在炎症（如风湿性关节炎、炎症性肠病、哮喘等）、细菌/病毒感染等相关疾病的 应用研究。迄今以通讯/第一作者在Chem. Soc. Rev., Prog. Polym. Sci., Acc. Chem. Res., Adv. Drug Deliv. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Commun., Adv. Mater. 等发表论文110余篇。所有论文共被引用12,000余次，H因子为58 (数据来源Google Scholar)。2022年开始连续入选全球前2%科学家年度影响力榜单和终身影响力榜单 (World’s Top 2% Scientists)。

主持国家杰出青年科学基金 (2024)、国家基金委优秀青年科学基金 (2017) 和面上项目多项，中国科学技术大学学术领军人才计划，作为项目骨干参与基金委重大项目和国家重点研发项目。曾入选海外高层次人才引进计划青年项目，获安徽省自然科学一等奖 (第二完成人)，第二届生物医用高分子材料大会青年学者优秀奖；入选Wiley China Highly Contribution Author 2023-2025。担任NPJ Soft Matter副主编，功能高分子学报编委，Chin. J. Polym. Sci./高分子学报/高分子通报三刊青年编委和Smart Molecules青年编委。

指导学生10余人次获得博士研究生国家奖学金，1人次获中科院院长奖。1人次获安徽省优秀毕业生，3人获校优秀毕业生。


Google Scholar: https://scholar.google.com/citations?user=0JoIesUAAAAJ&hl=en&cstart=60&pagesize=20

Publons：https://publons.com/researcher/2783084/jinming-hu/


实验室长期招收博士后，特任副研究员等科研人员，待遇从优，欢迎有化学、材料、生物医学等研究背景的博士联系。E-mail: jmhu@ustc.edu.cn 


部分代表性论文 (# 第一作者；*通讯作者）：

  1. H. C. Ding,# H. Z. Ding,# G. H. Gan, S. Y. Luo, S. Q. Zheng, Z. Q. Shen, Y. P. Zou,* S. Y. Liu,* J. M. Hu,* J-Aggregated Macrocyclic Photocatalysts Enable Nitric Oxide (NO)-Enhanced Near-Infrared Photocatalytic Tumor Therapy,  Angewandte Chemie International Edition, 2026, 65,  10.1002/anie.8769084. 

  2. J. J. Tan,# G. H. Liu,# J. Cheng,# Z. Y. Deng, G. Y. Zhang, D. E. Discher,*  J. M. Hu,* S. Y. Liu* Harnessing Chemical and Light Energy for Controlled Mechanical Deformation in Rigid Polymersomes, Journal of the American Chemical Society, 2026,  148, 10.1021/jacs.6c08276. https://pubs.acs.org/doi/10.1021/jacs.6c08276 1.gif

  3. W. J. Li, M. X. Hou, M. L. Chen, Z. H. He, J. L. Zhang, J. Cen,* J. M. Hu,* J. J. Tan,* Z. Y. Deng,* S. Y. Liu* Photoresponsive Discoidal Polymersomes With Tracelessly Crosslinkable Bilayers for Intracellular Drug Delivery, Angewandte Chemie International Edition, 2026, 65, e9958935. https://onlinelibrary.wiley.com/doi/10.1002/anie.9958935 

    anie73072-gra-0001-m.jpg

  4. Z. Q. Shen, S. Y. Luo, H. C. Ding, Y. Jin, Z. T. Zhou, Q. J. Ruan,  G. H. Gan, S. Y. Liu,* J. M. Hu,* Photocatalytic Activation Strategy for Sequential Prodrug Release to Overcome Resistant Biofilms, Journal of the American Chemical Society, 2026, 148, 11667–11682. https://pubs.acs.org/doi/full/10.1021/jacs.5c19856  

  5.  Y. B. Zhang,# J. Cen,# R. J. Li,# X. Zhou, M. X. Hou,  J. M. Hu,* S. Y. Liu, * Self-Immolative Nanotheranostics with Albumin-Guided Tumor Targeting for Oxidative Stress-Amplified Photodynamic Therapy,  Angewandte Chemie International Edition, 2026, 65, 10.1002/anie.202524115 (Hot paper)  http://doi.org/10.1002/anie.202524115 anie71822-gra-0001-m.jpg

  6. L. X. Guo,# Q. Q. Shi,#* J. Zhang, C. L. Yang, J. J. Tan, K. Y. Li,  J. M. Hu,* S. Y. Liu, * Sequence-Defined Oligourethane Isomeric Mixtures for Irreversible Encryption, Angewandte Chemie International Edition, 2026, 65, 10.1002/anie.9117281 https://onlinelibrary.wiley.com/doi/10.1002/anie.9117281 

    3.jpg

  7. J. Q. Zhang,# G. H. Gan,# C. C. Cao, S. Q. Zheng, P. Wang, X. S. Liu,* J. M. Hu,* Drug-caged drugs enable photocatalytic dual decaging of nitric oxide and anesthetics for antibacterial analgesia, Nature Communications, 2026, 10.1038/s41467-026-69624-5 https://www.nature.com/articles/s41467-026-69624-5 ff04cce9-9462-40c6-bff7-b7dd5b45efca.png

  8. S. S. Guo,# J. L. Fu,# S. F. Cui, J. M. Hu,* Z. Y. Deng,* S. Y. Liu, * Bioinspired Backbone Editing Strategies for Rewriting Synthetic Polymers, Angewandte Chemie International Edition, 2026, 65, e22451.  https://onlinelibrary.wiley.com/doi/10.1002/anie.202522451 

    5.jpg

  9. J. J. Tan,# J. Q. Zhang,# M. L. Chen,# J. Cen,# W. L. Wang, C. Y. You, X. L. Hu,*   J. M. Hu,* S. Y. Liu, * Meltable Polycarbonate Polymersomes as Photoresponsive Micro-Analgesia Pumps for Concurrent Tumor Therapy and Pain Relief, Angewandte Chemie International Edition,  2026, 65, e22563.  https://onlinelibrary.wiley.com/doi/10.1002/anie.202522563 (Hot paper)

      6.jpg

  10. Y. H. Zhang,# B. Shao,# K. Jiang, J. Cen, Y. Liu, J. J. Tan, L Zhang, K. Y. Li, C. Y.  You, Z. H. He, G. Y. Zhang, M. L. Chen,*  J. M. Hu,* S. Y. Liu, * Fluorinated Ionizable Lipids for Efficient Spleen-Targeted mRNA Delivery in Cancer Immunotherapy, Journal of the American Chemical Society 2025, 147, 41756–41767.  https://pubs.acs.org/doi/10.1021/jacs.5c13982  

  11. M. X. Hou,# W. J. Li,# J. Cen,# W. H. Pan,* Z. Y. Deng,* J. M. Hu,* S. Y. Liu, * Insight into Lysine Selection via Controlled Degradation of 2,4-Diaminobutyric Acid and Ornithine Polypeptides, Angewandte Chemie International Edition, 2025, 64, e202502629. https://onlinelibrary.wiley.com/doi/10.1002/anie.202502629  (HOT paper)  7.jpg

  12. T. F. Ma,# G. H. Gan,#  J. Cheng, Z. Q. Shen, G. Y. Zhang, S. Y. Liu, * J. M. Hu,* Engineered Probiotics Enables Targeted Gut Delivery of Dual Gasotransmitters for Inflammatory Bowel Disease Therapy, Angewandte Chemie International Edition, 2025, 64, e202502588. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202502588  8.jpg

  13. S. Tang,# X. H. Liang,# Y. Li,# Y. Y. Li, G. Luo*, J. M. Hu,* D. F. Chen* Vinylogous Anionic Ring-Opening Polymerization of Vinylidenecyclopropanes with Native C–H Bonds as the Dormant Species, Journal of The American Chemical Society, 2025, 147, 7196–7202. https://pubs.acs.org/doi/10.1021/jacs.4c17911  Figure 1

  14. R. D. Song,# J. J. Tan,# J. Cen, Z. W. Li, Y. B. Zhang, M. X. Hou, R. J. Li, L. Q. Tang,* J. M. Hu,* S. Y. Liu* Optimizing Surface Maleimide/cRGD Ratios Enhances Targeting Efficiency of cRGD-Functionalized Nanomedicines, Journal of The American Chemical Society, 2025, 147, 2889-2901. https://pubs.acs.org/doi/10.1021/jacs.4c17178

       Figure 1

  15. S. Q. Zheng,# S. S. Chen,# Y. Y. Li, M. J. Liao, X. H. Liang, K. Li, X. P. Li, J. M. Hu,* D. F. Chen* Monomer Design Enables Mechanistic Mapping of Anionic Ring-Opening Polymerization of Aromatic Thionolactones, Angewandte Chemie International Edition, 2025, 64, e202500581. https://onlinelibrary.wiley.com/doi/10.1002/anie.202500581 

     9.jpg

  16. M. L. Chen,# J. Cen,# Q. Q. Shi,# B. Shao, J. J. Tan, X. J. Ye, Z. H. He, Y. Liu, G. Y. Zhang, J. M. Hu,* J. Q. Bao,* S. Y. Liu* Ultrasound-Enhanced Spleen-Targeted mRNA Delivery via Fluorinated PEGylated Lipid Nanoparticles for Immunotherapy, Angewandte Chemie International Edition, 2025, 64, e202500878. (VIP paper)  https://onlinelibrary.wiley.com/doi/10.1002/anie.202500878 

      10.jpg

  17. Z. Q. Shen,# W. Jiang,# S. Q. Zheng, S. Y. Luo, Z. X. Guo, Q. Wang, Y. C. Wang,* J. M. Hu* Intracellular Co-Delivery of Carbon Monoxide and Nitric Oxide Induces Mitochondrial Apoptosis for Cancer Therapy, Angewandte Chemie International Edition, 2025, 64, e202419939. (VIP paper) https://onlinelibrary.wiley.com/doi/10.1002/anie.202419939 

     11.jpg

  18. J. Cen,# W. Liu,# J. Xu,# X. X. Wang, J. L. Zhang, J. Zhang, Z. Y. Deng,* C. G. Zhou,* J. M. Hu,* S. Y. Liu* Single-Component High‐Resolution Dual-Tone EUV Photoresists Based on Precision Self-Immolative Polymers, Angewandte Chemie International Edition, 2025, 64, e202415588. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202415588

      12.jpg

  19. W. H. Pan, L. Zhang,* L. Li, J. Cen, R. D. Song, C. Z. Song, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Engineering Semicarbazide-Bearing Polypeptide Conjugates for Efficient Tumor Chemotherapy and Imaging of Tumor Metastasis, Advanced Materials, 2024, 36, 2309315. https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adma.202309315

      13.jpg

  20. G. H. Gan, Z. Q. Shen, S. Q. Zheng, G. Y. Zhang, D. L. Yin,* S. Y. Liu,* J. M. Hu* Biomimetic Activation of N-Nitrosamides with Red Light-Triggered Nitric Oxide Release via Mediated Electron Transfer, Angewandte Chemie International Edition, 2024, 63, e202409981. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202409981  

    14.jpg

  21. M. D. Zhang, J. Cheng, Z. Q. Shen, P. Y. Lin, S. G. Ding,* J. M. Hu* A Single-Component Dual Donor Enables Ultrasound-Triggered Co-release of Carbon Monoxide and Hydrogen Sulfide, Angewandte Chemie International Edition, 2023, 62, e202314563. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202314563  15.jpg

  22. J. Cheng, G. H. Gan, S. Q. Zheng, G. Y. Zhang, C. Zhu,* S. Y. Liu,* J. M. Hu* Biofilm heterogeneity-adaptive photoredox catalysis enables red light-triggered nitric oxide release for combating drug-resistant infections, Nature Communications, 2023, 14, 7510. https://www.nature.com/articles/s41467-023-43415-8  16.png

  23. Q. Q. Shi,# C. Z. Song,# M. L. Chen, J. Xu, S. Q. Zheng, J. J. Tan, J. L. Zhang, N. Wang, J. M. Hu,* S. Y. Liu* Label-Free Quantification of Digital Nanorods Assembled from Discrete Oligourethane Amphiphiles, Journal of The American Chemical Society, 2023, 145 23176-23187. https://pubs.acs.org/doi/10.1021/jacs.3c07577  Figure 1

  24. J. Xu,# C. Z. Lv,# Q. Q. Shi, J. L. Zhang, N. Wang, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Controlled Self-Assembly of Discrete Amphiphilic Oligourethanes with a Cascade Self-Immolative Motif, Angewandte Chemie International Edition, 2023, 62, e202306119. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202306119  17.jpg

  25. Z. Q. Shen, S. Q. Zheng, Y. M. Fang, G. Y. Zhang, C. Zhu,* S. Y. Liu,* J. M. Hu* Overcoming the Oxygen Dilemma in Photoredox Catalysis: Near-Infrared (NIR) Light-Triggered Peroxynitrite Generation for Antibacterial Applications, Angewandte Chemie International Edition, 2023, 62, e202219153. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202219153  18.jpg

  26. Q. Q. Shi,# X. Zhou,# J. Xu, J. L. Zhang, N. Wang, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Dendritic Quaternary-Encoded Oligourethanes for Data Encryption, Angewandte Chemie International Edition 2022, 61, e202214695. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202214695

      19.jpg

  27. J. Cen,# X. J. Ye,# X. Liu, W. H. Pan, L. Zhang, G. Y. Zhang, N. A. He,* A. Z. Shen,* J. M. Hu,* S. Y. Liu* Fluorinated Copolypeptide-Stabilized Microbubbles with Maleimide-Decorated Surfaces as Long-Term Ultrasound Contrast Agents. Angewandte Chemie International Edition 2022, 61, e202209610.  https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202209610  20.jpg 

  28. X. Y. Bao,# S. Q. Zheng,# L. Zhang, A. Z. Shen,* G. Y. Zhang, S. Y. Liu,* J. M. Hu* Nitric Oxide-Releasing aza-BODIPY: A New Near-Infrared JAggregate with Multiple Antibacterial Modalities, Angewandte Chemie International Edition 2022, 61, e202207250. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202207250   21.jpg

  29. Z. H. Chen, S. Q. Zheng, Z. Q. Shen, J. Cheng, S. Y. Xiao,* G. Y. Zhang, S. Y. Liu,* J. M. Hu* Oxygen-Tolerant Photoredox Catalysis Triggers Nitric Oxide Release for Antibacterial Applications, Angewandte Chemie International Edition 2022, 61, e202204526. (Hot Paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202204526   22.jpg

  30. G. H. Liu, J. J. Tan, J. Cen, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Oscillating the local milieu of polymersome interiors via single input-regulated bilayer crosslinking and permeability tuning, Nature Communications 2022, 13, 585. https://www.nature.com/articles/s41467-022-28227-6

       23.png

  31. P. Li, Z. W. Sun, J. L. Chen, Y. Zuo, C. Y. Yu, X. N. Liu, Z. Y. Yang, L. H. Chen, E. G. Fu, W. H. Wang, J. C. Zhang, Z. Q. Liu,* J. M. Hu,* S. D. Zhang* Spontaneous Resolution of Racemic Cage-Catenanes via Diastereomeric Enrichment at the Molecular Level and Subsequent Narcissistic Self-Sorting at the Supramolecular Level, Journal of The American Chemical Society, 2022, 144, 1342-1350. https://pubs.acs.org/doi/10.1021/jacs.1c11452  

    Figure 1

  32. L. Gao, J. Cheng, Z. Q. Shen, G. Y. Zhang, S. Y. Liu,* J. M. Hu* Orchestrating Nitric Oxide and Carbon Monoxide Signaling Molecules for Synergistic Treatment of MRSA Infections, Angewandte Chemie International Edition, 2022, 61, e202112782. (Hot Paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202112782   23.jpg

  33. J. J. Tan,# Z. Y. Deng,# C. Z. Song, J. Xu, Y. B. Zhang, Y. Yu, J. M. Hu*, S. Y. Liu* Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification, Journal of the American Chemical Society, 2021, 143, 13738-13748. https://pubs.acs.org/doi/10.1021/jacs.1c05617 

  34. Z. Q. Shen, S. Q. Zheng, S. Y. Xiao*, R. A. Shen, S. Y. Liu,* J. M. Hu* Red Light-Mediated Photoredox Catalysis Enables Self-Reporting Nitric Oxide Release for Efficient Antibacterial Treatment, Angewandte Chemie International Edition, 2021, 60, 20452-20460. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202107155  24.jpg

  35. J. Cheng, G. H. Gan, Z. Q. Shen, L. Gao, G. Y. Zhang, J. M. Hu* Red Light-Triggered Intracellular Carbon Monoxide Release Enables Selective Eradication of MRSA Infection, Angewandte Chemie International Edition, 2021, 60, 13513-13520. (Hot Paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202104024  25.jpg

  36. S. Y. Tao,# J. Cheng#, G. Su, D. Li, Z. Q. Shen, F. H. Tao, T. You*, J. M. Hu* Breathing Micelles for Combinatorial Treatment of Rheumatoid Arthritis, Angewandte Chemie International Edition, 2020, 59, 21864-21869. (VIP paper, Selected as Inside Cover) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202010009    26.png

Educational Experience

  • 2007.9—2012.12，中国科学技术大学，博士学位

  • 2003.9—2007.7，合肥工业大学，学士学位

Work Experience

  • 2021.8-至今，中国科学技术大学高分子科学与工程系，教授

  • 2017.8-2021.7，中国科学技术大学高分子科学与工程系，特任教授

  • 2016.1—2017.7，中国科学技术大学高分子科学与工程系，特任研究员

  • 2013.8—2015.12，澳大利亚莫纳什大学，博士后

  • 2013.1—2013.7，澳大利亚新南威尔士大学，博士后

Other Contact Information:

  • ZipCode:

  • PostalAddress:

  • Email:

Research Focus

Copyright © 2013 University of Science and Technology of China.