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胡进明，中国科学技术大学高分子科学与工程系教授，博士生导师；中国科学技术大学附属第一医院（安徽省立医院）特聘专家。2007年本科毕业于合肥工业大学，2012年博士毕业于中国科学技术大学，导师刘世勇教授。2013-2015年分别在澳大利亚新南威尔士大学和莫纳什大学从事博士后研究，合作导师均为Thomas P Davis教授。2016年入职中国科学技术大学高分子科学与工程系，先后担任特任研究员、特任教授、教授。
主要从事高分子材料可控合成、自组装调控及其生物医学功能应用研究，近期研究集中在气体药物（一氧化氮、一氧化碳和硫化氢）递送高分子材料的可控合成及其在炎症（如风湿性关节炎、炎症性肠病、哮喘等）、细菌/病毒感染等相关疾病的应用研究。迄今以通讯/第一作者在Chem. Soc. Rev., Prog. Polym. Sci., Acc. Chem. Res., Adv. Drug Deliv. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Commun.，Adv. Mater. 等发表论文110余篇。所有论文共被引用11,000余次，H因子为56 (数据来源Google Scholar)。2022年开始连续入选全球前2%科学家年度影响力榜单和终身影响力榜单（World’s Top 2% Scientists）。
主持国家杰出青年科学基金 (2024)、国家基金委优秀青年科学基金 (2017) 和面上项目多项，中国科学技术大学学术领军人才计划，作为项目骨干参与基金委重大项目和国家重点研发项目。曾入选海外高层次人才引进计划青年项目，获安徽省自然科学一等奖 (第二完成人)，第二届生物医用高分子材料大会青年学者优秀奖。担任NPJ Soft Matter副主编，功能高分子学报编委，Chin. J. Polym. Sci./高分子学报/高分子通报三刊青年编委和Smart Molecules青年编委。
指导学生10余人次获得博士研究生国家奖学金，1人次获中科院院长奖。1人次获安徽省优秀毕业生，3人获校优秀毕业生。
Google Scholar: https://scholar.google.com/citations?user=0JoIesUAAAAJ&hl=en&cstart=60&pagesize=20
Publons：https://publons.com/researcher/2783084/jinming-hu/
实验室长期招收博士后，特任副研究员等科研人员，待遇从优，欢迎有化学、材料、生物医学等研究背景的博士联系。E-mail: jmhu@ustc.edu.cn
代表性论文(# 第一作者；*通讯作者）：
S. S. Guo,# J. L. Fu,# S. F. Cui, J. M. Hu,* Z. Y. Deng, S. Y. Liu, * Bioinspired Backbone Editing Strategies for Rewriting Synthetic Polymers, Angewandte Chemie International Edition, 2026, 65, e22451. https://onlinelibrary.wiley.com/doi/10.1002/anie.202522451
J. J. Tan,# J. Q. Zhang,# M. L. Chen,# J. Cen,# W. L. Wang, C. Y. You, X. L. Hu,* J. M. Hu,* S. Y. Liu, * Meltable Polycarbonate Polymersomes as Photoresponsive Micro-Analgesia Pumps for Concurrent Tumor Therapy and Pain Relief, Angewandte Chemie International Edition, 2026, 65, e22563. https://onlinelibrary.wiley.com/doi/10.1002/anie.202522563
Y. H. Zhang,# B. Shao,# K. Jiang, J. Cen, Y. Liu, J. J. Tan, L Zhang, K. Y. Li, C. Y. You, Z. H. He, G. Y. Zhang, M. L. Chen,* J. M. Hu,* S. Y. Liu, * Fluorinated Ionizable Lipids for Efficient Spleen-Targeted mRNA Delivery in Cancer Immunotherapy, Journal of the American Chemical Society 2025, 147, 41756–41767. https://pubs.acs.org/doi/10.1021/jacs.5c13982
M. X. Hou,# W. J. Li,# J. Cen,# W. H. Pan,* Z. Y. Deng,* J. M. Hu,* S. Y. Liu, * Insight into Lysine Selection via Controlled Degradation of 2,4-Diaminobutyric Acid and Ornithine Polypeptides, Angewandte Chemie International Edition, 2025, 64, e202502629. （HOT paper) https://onlinelibrary.wiley.com/doi/10.1002/anie.202502629
T. F. Ma,# G. H. Gan,# J. Cheng, Z. Q. Shen, G. Y. Zhang, S. Y. Liu, * J. M. Hu,* Engineered Probiotics Enables Targeted Gut Delivery of Dual Gasotransmitters for Inflammatory Bowel Disease Therapy, Angewandte Chemie International Edition, 2025, 64, e202502588. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202502588
S. Tang,# X. H. Liang,# Y. Li,# Y. Y. Li, G. Luo*, J. M. Hu,* D. F. Chen* Vinylogous Anionic Ring-Opening Polymerization of Vinylidenecyclopropanes with Native C–H Bonds as the Dormant Species, Journal of The American Chemical Society, 2025, 147, 7196–7202. https://pubs.acs.org/doi/10.1021/jacs.4c17911
R. D. Song,# J. J. Tan,# J. Cen, Z. W. Li, Y. B. Zhang, M. X. Hou, R. J. Li, L. Q. Tang,* J. M. Hu,* S. Y. Liu* Optimizing Surface Maleimide/cRGD Ratios Enhances Targeting Efficiency of cRGD-Functionalized Nanomedicines, Journal of The American Chemical Society, 2025, 147, 2889-2901. https://pubs.acs.org/doi/10.1021/jacs.4c17178
S. Q. Zheng,# S. S. Chen,# Y. Y. Li, M. J. Liao, X. H. Liang, K. Li, X. P. Li, J. M. Hu,* D. F. Chen* Monomer Design Enables Mechanistic Mapping of Anionic Ring-Opening Polymerization of Aromatic Thionolactones, Angewandte Chemie International Edition, 2025, 64, e202500581. https://onlinelibrary.wiley.com/doi/10.1002/anie.202500581
M. L. Chen,# J. Cen,# Q. Q. Shi,# B. Shao, J. J. Tan, X. J. Ye, Z. H. He, Y. Liu, G. Y. Zhang, J. M. Hu,* J. Q. Bao,* S. Y. Liu* Ultrasound-Enhanced Spleen-Targeted mRNA Delivery via Fluorinated PEGylated Lipid Nanoparticles for Immunotherapy, Angewandte Chemie International Edition, 2025, 64, e202500878. (VIP paper) https://onlinelibrary.wiley.com/doi/10.1002/anie.202500878
Z. Q. Shen,# W. Jiang,# S. Q. Zheng, S. Y. Luo, Z. X. Guo, Q. Wang, Y. C. Wang,* J. M. Hu* Intracellular Co-Delivery of Carbon Monoxide and Nitric Oxide Induces Mitochondrial Apoptosis for Cancer Therapy, Angewandte Chemie International Edition, 2025, 64, e202419939. (VIP paper) https://onlinelibrary.wiley.com/doi/10.1002/anie.202419939
J. Cen,# W. Liu,# J. Xu,# X. X. Wang, J. L. Zhang, J. Zhang, Z. Y. Deng,* C. G. Zhou,* J. M. Hu,* S. Y. Liu* Single-Component High‐Resolution Dual-Tone EUV Photoresists Based on Precision Self-Immolative Polymers, Angewandte Chemie International Edition, 2025, 64, e202415588. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202415588
W. H. Pan, L. Zhang,* L. Li, J. Cen, R. D. Song, C. Z. Song, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Engineering Semicarbazide-Bearing Polypeptide Conjugates for Efficient Tumor Chemotherapy and Imaging of Tumor Metastasis, Advanced Materials, 2024, 36, 2309315. https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adma.202309315
G. H. Gan, Z. Q. Shen, S. Q. Zheng, G. Y. Zhang, D. L. Yin,* S. Y. Liu,* J. M. Hu* Biomimetic Activation of N-Nitrosamides with Red Light-Triggered Nitric Oxide Release via Mediated Electron Transfer, Angewandte Chemie International Edition, 2024, 63, e202409981. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202409981
M. D. Zhang, J. Cheng, Z. Q. Shen, P. Y. Lin, S. G. Ding,* J. M. Hu* A Single-Component Dual Donor Enables Ultrasound-Triggered Co-release of Carbon Monoxide and Hydrogen Sulfide, Angewandte Chemie International Edition, 2023, 62, e202314563. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202314563
J. Cheng, G. H. Gan, S. Q. Zheng, G. Y. Zhang, C. Zhu,* S. Y. Liu,* J. M. Hu* Biofilm heterogeneity-adaptive photoredox catalysis enables red light-triggered nitric oxide release for combating drug-resistant infections, Nature Communications, 2023, 14, 7510. https://www.nature.com/articles/s41467-023-43415-8
Q. Q. Shi,# C. Z. Song,# M. L. Chen, J. Xu, S. Q. Zheng, J. J. Tan, J. L. Zhang, N. Wang, J. M. Hu,* S. Y. Liu* Label-Free Quantification of Digital Nanorods Assembled from Discrete Oligourethane Amphiphiles, Journal of The American Chemical Society, 2023, 145 23176-23187. https://pubs.acs.org/doi/10.1021/jacs.3c07577
J. Xu,# C. Z. Lv,# Q. Q. Shi, J. L. Zhang, N. Wang, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Controlled Self-Assembly of Discrete Amphiphilic Oligourethanes with a Cascade Self-Immolative Motif, Angewandte Chemie International Edition, 2023, 62, e202306119. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202306119
Z. Q. Shen, S. Q. Zheng, Y. M. Fang, G. Y. Zhang, C. Zhu,* S. Y. Liu,* J. M. Hu* Overcoming the Oxygen Dilemma in Photoredox Catalysis: Near-Infrared (NIR) Light-Triggered Peroxynitrite Generation for Antibacterial Applications, Angewandte Chemie International Edition, 2023, 62, e202219153. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202219153
Q. Q. Shi,# X. Zhou,# J. Xu, J. L. Zhang, N. Wang, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Dendritic Quaternary-Encoded Oligourethanes for Data Encryption, Angewandte Chemie International Edition 2022, 61, e202214695. (Hot paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202214695
J. Cen,# X. J. Ye,# X. Liu, W. H. Pan, L. Zhang, G. Y. Zhang, N. A. He,* A. Z. Shen,* J. M. Hu,* S. Y. Liu* Fluorinated Copolypeptide-Stabilized Microbubbles with Maleimide-Decorated Surfaces as Long-Term Ultrasound Contrast Agents. Angewandte Chemie International Edition 2022, 61, e202209610. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202209610
X. Y. Bao,# S. Q. Zheng,# L. Zhang, A. Z. Shen,* G. Y. Zhang, S. Y. Liu,* J. M. Hu* Nitric Oxide-Releasing aza-BODIPY: A New Near-Infrared JAggregate with Multiple Antibacterial Modalities, Angewandte Chemie International Edition 2022, 61, e202207250. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202207250
Z. H. Chen, S. Q. Zheng, Z. Q. Shen, J. Cheng, S. Y. Xiao,* G. Y. Zhang, S. Y. Liu,* J. M. Hu* Oxygen-Tolerant Photoredox Catalysis Triggers Nitric Oxide Release for Antibacterial Applications, Angewandte Chemie International Edition 2022, 61, e202204526. (Hot Paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202204526
G. H. Liu, J. J. Tan, J. Cen, G. Y. Zhang, J. M. Hu,* S. Y. Liu* Oscillating the local milieu of polymersome interiors via single input-regulated bilayer crosslinking and permeability tuning, Nature Communications 2022, 13, 585. https://www.nature.com/articles/s41467-022-28227-6
P. Li, Z. W. Sun, J. L. Chen, Y. Zuo, C. Y. Yu, X. N. Liu, Z. Y. Yang, L. H. Chen, E. G. Fu, W. H. Wang, J. C. Zhang, Z. Q. Liu,* J. M. Hu,* S. D. Zhang* Spontaneous Resolution of Racemic Cage-Catenanes via Diastereomeric Enrichment at the Molecular Level and Subsequent Narcissistic Self-Sorting at the Supramolecular Level, Journal of The American Chemical Society, 2022, 144, 1342-1350. https://pubs.acs.org/doi/10.1021/jacs.1c11452
L. Gao, J. Cheng, Z. Q. Shen, G. Y. Zhang, S. Y. Liu,* J. M. Hu* Orchestrating Nitric Oxide and Carbon Monoxide Signaling Molecules for Synergistic Treatment of MRSA Infections, Angewandte Chemie International Edition, 2022, 61, e202112782. (Hot Paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202112782
J. J. Tan,# Z. Y. Deng,# C. Z. Song, J. Xu, Y. B. Zhang, Y. Yu, J. M. Hu*, S. Y. Liu* Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification, Journal of the American Chemical Society, 2021, 143, 13738-13748. https://pubs.acs.org/doi/10.1021/jacs.1c05617
Z. Q. Shen, S. Q. Zheng, S. Y. Xiao*, R. A. Shen, S. Y. Liu,* J. M. Hu* Red Light-Mediated Photoredox Catalysis Enables Self-Reporting Nitric Oxide Release for Efficient Antibacterial Treatment, Angewandte Chemie International Edition, 2021, 60, 20452-20460. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202107155
J. Cheng, G. H. Gan, Z. Q. Shen, L. Gao, G. Y. Zhang, J. M. Hu* Red Light-Triggered Intracellular Carbon Monoxide Release Enables Selective Eradication of MRSA Infection, Angewandte Chemie International Edition, 2021, 60, 13513-13520. (Hot Paper) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202104024
S. Y. Tao,# J. Cheng#, G. Su, D. Li, Z. Q. Shen, F. H. Tao, T. You*, J. M. Hu* Breathing Micelles for Combinatorial Treatment of Rheumatoid Arthritis, Angewandte Chemie International Edition, 2020, 59, 21864-21869. (VIP paper, Selected as Inside Cover) https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202010009