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Wang Dongdong


Supervisor of Doctorate Candidates


Administrative Position:Specialized Researcher

Business Address:中国科学技术大学东校区 理化大楼5001

Contact Information:wangdongdong@ustc.edu.cn

Alma Mater:University of Science and Technology of China

Discipline:Materials Science and Engineering
Biomedical Engineering


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中国科学技术大学,特任教授,博士生导师,中国科学院人才计划。近年来在国际学术期刊发表论文60余篇,包括Nat. Rev. Chem.Acc. Chem. Res.Nat. Commun.J. Am. Chem. Soc.Angew. Chem. Int. Ed.Adv. Mater.ChemACS NanoAdv. Sci.Small, BiomaterialsChem. Mater. 等,多篇代表作入选ESI高被引论文,并被亚洲科学家杂志、科学网等媒体以亮点形式报道。曾获宝钢教育奖学金、研究生国家奖学金、苏州育才奖学金、安徽省品学兼优毕业生等。受邀担任国际知名期刊的独立审稿人,包括Nat. Commun., JACS, ACS Nano, Biomaterials, Small等。受邀担任Frontiers in Chemistry及Molecules的客座编辑。

Group Homepagehttp:///www.fnl.ustc.edu.cn     ORCID0000-0002-6278-0706



  [1] 课题组常年开放特任副研究员博士后(要求:取得即将取得博士学位)职位申请,欢迎具有材料科学与工程、无机化学、生物化学、生物医学工程、药学等专业背景的学生加入~  招聘详情见:https://employment.ustc.edu.cn/cn/indexnews.aspx?sign=635487875427187007 

  [2] 课题组每年招收硕博连读生2名,欢迎对本课题组研究工作感兴趣的同学加入~


  1. Wang, D., Liu, J., Wang, C., Zhang, W., Yang, G., Chen, Y., Zhang, X., Wu, Y., Gu, L., Chen, H., Yuan, W., Chen, X., Liu, G., Gao, B., Chen, Q. W., Zhao, Y. L.* Microbial Synthesis of Prussian Blue for Potentiating Checkpoint Blockade Immunotherapy. Nat. Commun., 2023, 14, 2943. Link

  2. Wang, D.*, Zhang, L., Wang, C., Cheng, Z., Zheng, W., Xu, P., Chen, Q. W.*, Zhao, Y. L.* Missing-Linker-Confined Single-Atomic Pt Nanozymes for Enzymatic Theranostics of Tumor. Angew. Chem. Int. Ed., 2023, 62, e202217995Link

  3. Bindra, A., Wang, D.*, Zhao, Y. L.* Metal‐Organic Frameworks Meet Polymers: From Synthesis Strategies to Healthcare Applications. Adv. Mater., 2023, 35, 2300700. Link

  4. Wang, D., Wu, H., Phua, F., Lim, W., Yang, G., Lim, W., Gu, L., Qian, C., Wang, H., Guo, Z.*, Chen, H., Zhao, Y. L.* Self-Assembled Single-Atom Nanozyme for Enhanced Photodynamic Therapy Treatment of Tumor. Nat. Commun., 2020, 11, 357. Link (ESI 1% highly cited)

  5. Wang, D., Jana, D., Zhao, Y. L.* Metal-Organic Framework Derived Nanozymes in Biomedicine. Acc. Chem. Res., 2020, 53, 1389-1400. Link (ESI 1% highly cited)

  6. Wang, D., Wu, H., Lim, W., Phua, F., Xu, P., Chen, Q. W.*, Guo, Z.*, Zhao, Y. L.* A Mesoporous Nanoenzyme Derived from Metal-Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy. Adv. Mater., 2019, 31, 1901893. Link (ESI 1% highly cited)

  7. Wang, D., Zhao, Y. L.* Single-Atom Engineering of Metal-Organic Framework Toward Healthcare. Chem, 2021, 7, 2635-2671. Link

  8. Wang, D., He, W., Liu, J., Jana, D., Wu, Y., Zhang, X., Qian, C., Guo, Y., Chen, X., Bindra, A., Zhao, Y. L.* Missing-Linker-Assisted Artesunate Delivery by Metal-Organic Frameworks for Synergistic Cancer Treatment. Angew. Chem. Int. Ed., 2021, 60, 26254-26259. Link

  9. Wang, D., Wu, H., Wang, C., Gu, L., Chen, H., Jana, D., Wang, X., Xu, P., Guo, Z.*, Chen, Q. W.*, Zhao, Y. L.* Self-Assembly Single-Site Nanozyme for Tumor-Specific Amplified Cascade Enzymatic Therapy. Angew. Chem. Int. Ed., 2021, 60, 3001-3007. Link (ESI 1% highly cited)

  10. Wang, D., Wu, H., Yang, G., Qian, C., Gu, L., Wang, H., Zhou, W., Liu, J., Guo, Z.*, Chen, H., Jana, D., Zhao, Y. L.* Metal-Organic Framework Derived Multicomponent Nanoagent as a Reactive Oxygen Species Amplifier for Enhanced Photodynamic Therapy. ACS Nano, 2020, 14, 13500-13511. Link

  11. Jana, D.#Wang, D.#, Bindra, A., Guo, Y.,  Liu, J., Zhao, Y. L.* Ultrasmall Alloy Nanozyme for Ultrasound- and Near-Infrared Light-Promoted Tumor Ablation. ACS Nano, 2021, 15, 7774-7782. Link (ESI 1% highly cited)

  12. Wang, C.#Wang, D.#, Liu, S., Jiang, P., Lin, Z., Xu, P., Yang, K., Lu, J., Tong, H., Hu, L., Zhang, W., Chen, Q. W.* Engineering the Coordination Environment Enables Molybdenum Single-Atom Catalyst for Efficient Oxygen Reduction Reaction. J. Catal., 2020, 389, 150-156. Link

  13. Wang, D., Wu, H., Zhou, J., Xu, P., Wang, C., Shi, R., Wang, H.*, Guo, Z.*, Chen, Q. W.* In Situ One-Pot Synthesis of MOF-Polydopamine Hybrid Nanogels with Enhanced Photothermal Effect for Targeted Cancer TherapyAdv. Sci., 2018, 5, 1800287. Link

  14. Wang, D., Shi, R., Zhou, J., Shi, S., Wu, H., Xu, P., Wang, H.*, Xia, G., Barnhart, T. E., Cai, W. B.*, Guo, Z.*, Chen, Q. W.* Photo-Enhanced Singlet Oxygen Generation of Prussian Blue-Based Nanocatalyst for Augmented Photodynamic Therapy. iScience. 2018, 9, 14-26. Link

  15. Qian, C., Feng, L., Teo, W., Liu, J., Zhou, W., Wang, D., Zhao, Y. L.* Imine and Imine-Derived Linkages in Two-Dimensional Covalent Organic Frameworks. Nat. Rev. Chem., 2022, 6, 881-898.  Link

  16. Wu, Y., Sun, L., Chen, X., Liu, J., Ouyang, J., Zhang, X., Guo, Y., Chen, Y., Yuan, W., Wang, D., He, T., Zeng, F., Chen, H. Z.*, Wu, S. Z.*, Zhao, Y. L.* Cucurbit[8]uril-Based Water-Dispersible Assemblies with Enhanced Pptoacoustic Performance for Multispectral Optoacoustic Imaging. Nat. Commun., 2023, 14, 3918. Link

  17. Zhao, Y., Song, S., Wang, D., Liu, H., Zhang, J., Li, Z. H.*, Wang, J. C.*, Ren, X. Z.*, Zhao, Y. L.* Nanozyme-Reinforced Hydrogel as A H2O2-Driven Oxygenerator for Enhancing Prosthetic Interface Osseointegration in Rheumatoid Arthritis Therapy. Nat. Commun., 2022, 13, 6758. Link

  18. Liu, J., You, F., He, B., Wu, Y., Wang, D., Zhou, W., Qian, C., Yang, G., Liu, G., Wang, H., Guo, Y., Gu, L., Feng, L. Li, S. Z., Zhao, Y. L.* Directing the Architecture of Surface-Clean Cu2O for CO Electroreduction. J. Am. Chem. Soc., 2022, 144, 12410-12420. Link

  19. Chen, Y., He, P., Jana, D., Wang, D., Wang, M., Yu, P., Zhu, W.*, Zhao, Y. L.* Glutathione-Depleting Organic Metal Adjuvants for Effective NIR-II Photothermal Immunotherapy. Adv. Mater., 2022, 34, 2201706. Link

  20. Yang, G., Wang, D., Phua, F., Bindra, A., Qian, C., Zhang, R., Cheng, L., Liu, G., Wu, H., Liu, Z.*, Zhao, Y. L.* Albumin-Based Therapeutics Capable of Glutathione Consumption and Hydrogen Peroxide Generation for Synergetic Chemodynamic and Chemotherapy of Cancer. ACS Nano, 2022, 16, 2319-2329. Link

  21. Gu, L., Ye, W., Liang, X., Lv, A., Ma, H., Singh, M., Jia, W., Shen, Z., Guo, Y., Gao, Y., Chen, H., Wang, D., Wu, Y., Liu, J., Wang, H., Zheng, Y.-X., An, Z. F.*, Huang, W.*, Zhao, Y. L.* Circularly Polarized Organic Room Temperature Phosphorescence from Amorphous Copolymers. J. Am. Chem. Soc., 2021, 143, 18527-18535. Link

  22. Zhang, X., Chen, X., Guo, Y., Gao, G., Wang, D., Wu, Y., Liu, J., Liang, G. L., Zhao, Y. L.*, Wu, F.-G.* Dual Gate-Controlled Therapeutics for Overcoming Bacterium-Induced Drug Resistance and Potentiating Cancer Immunotherapy. Angew. Chem. Int. Ed., 2021, 60, 14013-14021. Link

  23. Zhang, W., Liu, J., Li, X., Zheng, Y., Chen, L., Wang, D., Foda, M. F., Ma, Z., Zhao, Y. L.*, Han, H. Y.* Precise Chemodynamic Therapy of Cancer by Trifunctional Bacterium-Based Nanozymes. ACS Nano, 2021, 15, 19321-19333. Link

  24. Feng, L., Liu, B., Xie, R., Wang, D., Qian, C., Zhou, W., Liu, J., Jana, D., Yang, P. P.*, Zhao, Y. L.* An Ultrasmall SnFe2O4 Nanozyme with Endogenous Oxygen Generation and Glutathione Depletion for Synergistic Cancer Therapy. Adv. Funct. Mater., 2021, 31, 2006216. Link

  25. Qian, C., Zhou, W., Qiao, J., Wang, D., Li, X., Teo, W., Shi, X., Wu, H., Di, J., Wang, H., Liu, G., Gu, L., Liu, J., Feng, L., Liu, Y., Quek, S., Loh, K. P., Zhao, Y. L.* Linkage Engineering by Harnessing Supramolecular Interactions to Fabricate 2D Hydrazone-Linked Covalent Organic Framework Platforms toward Advanced Catalysis. J. Am. Chem. Soc., 2020, 142, 18138-18149. Link

  26. Wang, H., Qian, C., Liu, J., Zeng, Y., Wang, D., Zhou, W., Gu, L., Wu, H., Liu, G., Zhao, Y. L.* Integrating Suitable Linkage of Covalent Organic Frameworks into Covalently Bridged Inorganic/Organic Hybrids toward Efficient Photocatalysis. J. Am. Chem. Soc., 2020, 142, 4862-4871. Link

  27. Gu, L., Wu, H., Ma, H., Ye, W., Jia, W., Wang, H., Chen, H., Zhang, N., Wang, D., Qian, C., An, Z. F.*, Huang, W.*, Zhao, Y. L.* Color-Tunable Ultralong Organic Room Temperature Phosphorescence from A Multicomponent Copolymer. Nat. Commun., 2020, 11, 944. Link

  28. Wang, P., Yang, Y.*, Zheng, W., Cheng, Z., Wang, C., Chen, S., Wang, D., Yang, J., Shi, H., Meng, P., Wang, P., Tong, H., Chen, J., Chen, Q. W.* V–O Species-Doped Carbon Frameworks Loaded with Ru Nanoparticles as Highly Efficient and CO-Tolerant Catalysts for Alkaline Hydrogen Oxidation. J. Am. Chem. Soc., 2023, 145, 27867-27876. Link

  29. Zhao, Y., Wang, D., Qian, T., Zhang, J., Li, Z.*, Gong, Q.*, Ren, X.*, Zhao, Y. L.* Biomimetic Nanozyme-Decorated Hydrogels with H2O2-Activated Oxygenation for Modulating Immune Microenvironment in Diabetic Wound. ACS Nano, 2023, 17, 16854-16869Link

  30. Tu, J., Tong, H., Wang, P., Wang, D., Yang, Y., Meng, X., Hu, L., Wang, H.*, Chen, Q. W.* Octahedral/Tetrahedral Vacancies in Fe3O4 as K-Storage Sites: A Case of Anti-Spinel Structure Material Serving as High-Performance Anodes for PIBs. Small, 2023, 19, 2301606. Link

  31. Yang, G., Bindra, A., Phua, F., Liu, J., Wu, H., Wang, D., Qian, C., Liu, G., Zhao, Y. L.* Light-Triggered Hypoxia-Responsive Nanoscale Metal-Organic Frameworks for Highly Efficient Antitumor Treatment. Adv. Optical Mater., 2023, 11, 2201043. Link

Educational Experience

  • 2013.9 -- 2018.6

    University of Science and Technology of China       Material Physics and Chemistry       With Certificate of Graduation for Doctorate Study       Doctoral Degree in Philosophy      导师:陈乾旺 教授(杰青/长江学者),http://fnl.ustc.edu.cn/(中国科大功能纳米实验室),博士论文:MOFs杂化纳米材料在纳米医学中的应用研究

  • 2009.9 -- 2013.6

    Lanzhou University       Material Science       With Certificate of Graduation for Study as Master's Candidates       Master's Degree      导师:王育华 教授(杰青) ,https://www.lzu.edu.cn/static/z/447.html,本科论文:铕掺杂氧化石墨烯光致发光性能研究。 导师:秦勇 教授(长江学者),http://yqin.lzu.edu.cn/,创新计划课题:熔融盐法制备ZnO纳米线阵列。

Work Experience

  • 2023.11 -- Now

    中国科学技术大学      合肥微尺度物质科学国家研究中心      特任教授

  • 2022.6 -- 2023.11

    University of Science and Technology of China      Hefei National Research Center for Physical Sciences at the Microscale      特任研究员

  • 2018.10 -- 2022.6

    Nanyang Technological University      School of Chemistry, Chemical Engineering and Biotechnology      博士后研究员      Advisor: Prof. Yanli Zhao (Lee Soo Ying Professorship 赵彦利 教授)
    Web: personal.ntu.edu.sg/zhaoyanli/home.html

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Research Group

Name of Research Group:中国科大功能纳米实验室——生物医学研究组(FNL-BioNano)

Description of Research Group:我们研究组是中国科大功能纳米实验室(实验室主页:http://fnl.ustc.edu.cn/)下的一个研究组,我们的研究聚焦于功能纳米材料在疾病诊断与治疗、抑菌抗菌、生物传感、环境保护等健康相关领域的应用研究。在基础研究的同时,我们将致力于以生命健康应用为导向,发挥所在国家研究中心和实验室的优势,将纳米材料功能化,智能化。