中国科学技术大学特任研究员，正高，博士生导师。在国际学术期刊发表论文50余篇，包括Nat. Rev. Chem.、Acc. Chem. Res.、Nat. Commun.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Adv. Mater.、Chem、ACS Nano、Adv. Sci.、Small、Biomaterials、Chem. Mater.等，多篇代表作入选ESI高被引论文，并被亚洲科学家杂志、科学网等媒体以亮点形式报道。曾获宝钢教育奖学金，研究生国家奖学金，苏州育才奖学金，安徽省品学兼优毕业生等。受邀担任国际知名期刊的独立审稿人，包括Nat. Commun.、JACS、Biomaterials、Small等。受邀担任Frontiers in Chemistry及Molecules的客座编辑。

个人主页：http://www.hfnl.ustc.edu.cn/page?catid=73

个人主页：https://orcid.org/0000-0002-6278-0706

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课题组常年开放博士后（要求：取得或即将取得博士学位）职位申请，欢迎具有材料科学与工程、无机化学、生物化学、生物医学工程、药学等专业背景的同学加入~

课题组每年招收博士研究生1-2名，欢迎对本课题组研究工作感兴趣的同学加入~

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代表性论文

[1] Wang, D., Liu, J., Wang, C., Zhang, W., Yang, G., Chen, Y., Zhang, X., Wu, Y., Gu, L., Chen, H., Yuan, W., Chen, X., Liu, G., Gao, B., Chen, Q. W., Zhao, Y. L.* Microbial synthesis of Prussian blue for potentiating checkpoint blockade immunotherapy. Nat. Commun., 2023, (Accepted).

[2] Wang, D.*, Zhang, L., Wang, C., Cheng, Z., Zheng, W., Xu, P., Chen, Q. W.*, Zhao, Y. L.* Missing-Linker-Confined Single-Atomic Pt Nanozymes for Enzymatic Theranostics of Tumor. Angew. Chem. Int. Ed., 2023, 62, e202217995.

[3] Bindra, A., Wang, D.*, Zhao, Y. L.* Metal‐Organic Frameworks Meet Polymers: From Synthesis Strategies to Healthcare Applications. Adv. Mater., 2023, doi: 10.1002/adma.202300700.

[4] Wang, D., Wu, H., Phua, F., Lim, W., Yang, G., Lim, W., Gu, L., Qian, C., Wang, H., Guo, Z.*, Chen, H., Zhao, Y. L.* Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor. Nat. Commun., 2020, 11, 357.  (ESI 1% highly cited)

[5] Wang, D., Jana, D., Zhao, Y. L.* Metal-Organic Framework Derived Nanozymes in Biomedicine. Acc. Chem. Res., 2020, 53, 1389-1400.  (ESI 1% highly cited)

[6] Wang, D., Wu, H., Lim, W., Phua, F., Xu, P., Chen, Q. W.*, Guo, Z.*, Zhao, Y. L.* A Mesoporous Nanoenzyme Derived from Metal-Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy. Adv. Mater., 2019, 31, 1901892.  (ESI 1% highly cited)

[7] Wang, D., Zhao, Y. L.* Single-Atom Engineering of Metal-Organic Framework Toward Healthcare. Chem, 2021, 7, 2635-2671.

[8] Wang, D., He, W., Liu, J., Jana, D., Wu, Y., Zhang, X., Qian, C., Guo, Y., Chen, X., Bindra, A., Zhao, Y. L.* Missing-Linker-Assisted Artesunate Delivery by Metal-Organic Frameworks for Synergistic Cancer Treatment. Angew. Chem. Int. Ed., 2021, 60, 26254-26259.

[9] Wang, D., Wu, H., Wang, C., Gu, L., Chen, H., Jana, D., Wang, X., Xu, P., Guo, Z.*, Chen, Q. W.*, Zhao, Y. L.* Self-Assembly Single-Site Nanozyme for Tumor-Specific Amplified Cascade Enzymatic Therapy. Angew. Chem. Int. Ed., 2021, 60, 3001-3007.  (ESI 1% highly cited)

[10] Wang, D., Wu, H., Yang, G., Qian, C., Gu, L., Wang, H., Zhou, W., Liu, J., Guo, Z.*, Chen, H., Jana, D., Zhao, Y. L.* Metal-Organic Framework Derived Multicomponent Nanoagent as a Reactive Oxygen Species Amplifier for Enhanced Photodynamic Therapy. ACS Nano, 2020, 14, 13500-13511.

[11] Jana, D.^#, Wang, D.^#, Bindra, A., Guo, Y.,  Liu, J., Zhao, Y. L.* Ultrasmall Alloy Nanozyme for Ultrasound- and Near-Infrared Light-Promoted Tumor Ablation. ACS Nano, 2021, 15, 7774-7782.  (ESI 1% highly cited)

[12] Wang, D., Wu, H., Zhou, J., Xu, P., Wang, C., Shi, R., Wang, H.*, Guo, Z.*, Chen, Q. W.* In Situ One-Pot Synthesis of MOF-Polydopamine Hybrid Nanogels with Enhanced Photothermal Effect for Targeted Cancer Therapy. Adv. Sci., 2018, 5, 1800287.

[13] Wang, D., Shi, R., Zhou, J., Shi, S., Wu, H., Xu, P., Wang, H.*, Xia, G., Barnhart, T. E., Cai, W. B.*, Guo, Z.*, Chen, Q. W.* Photo-enhanced singlet oxygen generation of prussian blue-based nanocatalyst for augmented photodynamic therapy. iScience. 2018, 9, 14-26.

[14] Qian, C., Feng, L., Teo, W., Liu, J., Zhou, W., Wang, D., Zhao, Y. L.* Imine and imine-derived linkages in two-dimensional covalent organic frameworks. Nat. Rev. Chem., 2022, 6, 881-898.

[15] Zhao, Y., Song, S., Wang, D., Liu, H., Zhang, J., Li, Z. H.*, Wang, J. C.*, Ren, X. Z.*, Zhao, Y. L.* Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy. Nat. Commun., 2022, 13, 6758.

[16] Liu, J., You, F., He, B., Wu, Y., Wang, D., Zhou, W., Qian, C., Yang, G., Liu, G., Wang, H., Guo, Y., Gu, L., Feng, L. Li, S. Z., Zhao, Y. L.* Directing the Architecture of Surface-Clean Cu2O for CO Electroreduction. J. Am. Chem. Soc., 2022, 144, 12410-12420.

[17] Chen, Y., He, P., Jana, D., Wang, D., Wang, M., Yu, P., Zhu, W.*, Zhao, Y. L.* Glutathione-Depleting Organic Metal Adjuvants for Effective NIR-II Photothermal Immunotherapy. Adv. Mater., 2022, 34, 2201706.

[18] Yang, G., Wang, D., Phua, F., Bindra, A., Qian, C., Zhang, R., Cheng, L., Liu, G., Wu, H., Liu, Z.*, Zhao, Y. L.* Albumin-Based Therapeutics Capable of Glutathione Consumption and Hydrogen Peroxide Generation for Synergetic Chemodynamic and Chemotherapy of Cancer. ACS Nano, 2022, 16, 2319-2329.

[19] Gu, L., Ye, W., Liang, X., Lv, A., Ma, H., Singh, M., Jia, W., Shen, Z., Guo, Y., Gao, Y., Chen, H., Wang, D., Wu, Y., Liu, J., Wang, H., Zheng, Y.-X., An, Z. F.*, Huang, W.*, Zhao, Y. L.* Circularly Polarized Organic Room Temperature Phosphorescence from Amorphous Copolymers. J. Am. Chem. Soc., 2021, 143, 18527-18535.

[20] Zhang, X., Chen, X., Guo, Y., Gao, G., Wang, D., Wu, Y., Liu, J., Liang, G. L., Zhao, Y. L.* Wu, F.-G.* Dual Gate-Controlled Therapeutics for Overcoming Bacterium-Induced Drug Resistance and Potentiating Cancer Immunotherapy. Angew. Chem. Int. Ed., 2021, 60, 14013-14021.

[21] Zhang, W., Liu, J., Li, X., Zheng, Y., Chen, L., Wang, D., Foda, M. F., Ma, Z., Zhao, Y. L.*, Han, H. Y.* Precise Chemodynamic Therapy of Cancer by Trifunctional Bacterium-Based Nanozymes. ACS Nano, 2021, 15, 19321-19333.

[22] Feng, L., Liu, B., Xie, R., Wang, D., Qian, C., Zhou, W., Liu, J., Jana, D., Yang, P. P.*, Zhao, Y. L.* An Ultrasmall SnFe2O4 Nanozyme with Endogenous Oxygen Generation and Glutathione Depletion for Synergistic Cancer Therapy. Adv. Funct. Mater., 2021, 31, 2006216.

[23] Qian, C., Zhou, W., Qiao, J., Wang, D., Li, X., Teo, W., Shi, X., Wu, H., Di, J., Wang, H., Liu, G., Gu, L., Liu, J., Feng, L., Liu, Y., Quek, S., Loh, K. P., Zhao, Y. L.* Linkage Engineering by Harnessing Supramolecular Interactions to Fabricate 2D Hydrazone-Linked Covalent Organic Framework Platforms toward Advanced Catalysis. J. Am. Chem. Soc., 2020, 142, 18138-18149.

[24] Wang, H., Qian, C., Liu, J., Zeng, Y., Wang, D., Zhou, W., Gu, L., Wu, H., Liu, G., Zhao, Y. L.* Integrating Suitable Linkage of Covalent Organic Frameworks into Covalently Bridged Inorganic/Organic Hybrids toward Efficient Photocatalysis. J. Am. Chem. Soc., 2020, 142, 4862-4871.

[25] Gu, L., Wu, H., Ma, H., Ye, W., Jia, W., Wang, H., Chen, H., Zhang, N., Wang, D., Qian, C., An, Z. F.*, Huang, W.*, Zhao, Y. L.* Color-tunable ultralong organic room temperature phosphorescence from a multicomponent copolymer. Nat. Commun., 2020, 11, 944.