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  • 汪冬冬 ( 特任教授 )

    的个人主页 http://faculty.ustc.edu.cn/wangdd/zh_CN/index.htm

  •   特任教授   博士生导师
个人首页 当前位置： 中文主页 >> 个人首页


个人概况        

中国科学技术大学，特任教授，博士生导师，入选国家级海外高层次人才引进计划（青年项目）、中国科学院率先行动人才计划B类（择优支持）。近年来在国际学术期刊发表论文60余篇，包括Nat. Rev. Chem., Acc. Chem. Res., Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Adv. Mater., Chem, ACS Nano, Adv. Sci., Small, Biomaterials, Chem. Mater. 等，多篇代表作入选ESI高被引论文，并被亚洲科学家杂志、科学网等媒体以亮点形式报道，JMCB Emerging Investigators 2024。曾获宝钢教育奖学金、研究生国家奖学金、苏州育才奖学金、安徽省品学兼优毕业生等。受邀担任国际知名期刊的独立审稿人，包括Nat. Commun., JACS, ACS Nano, Biomaterials, Small等。

Team Homepage：http:///www.fnl.ustc.edu.cn     Personal Page：https://www.hfnl.ustc.edu.cn/detail?t=1&id=20083     ORCID：0000-0002-6278-0706

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招生招聘        

[1] 课题组每年招收硕博连读生2名，欢迎对本课题组研究工作感兴趣的同学加入。

[2] 课题组常年开放特任副研究员和博士后职位申请，欢迎具有材料科学与工程、无机化学、生物化学、生物医学工程、药学等专业背景的学生加入~                   招聘详情见：https://employment.ustc.edu.cn/cn/indexnews.aspx?sign=635487875427187007 。


工作经历        

2023.12 -- 至今            中国科学技术大学         合肥微尺度物质科学国家研究中心      特任教授

2022.06 -- 2023.11      中国科学技术大学         合肥微尺度物质科学国家研究中心      特任研究员

2018.10 -- 2022.06      新加坡南洋理工大学      化学、化学工程与生物技术学院         博士后（Advisor: 赵彦利 教授）


学习经历        

2013.09 -- 2018.06      中国科学技术大学         合肥微尺度物质科学国家研究中心      工学博士（Advisor: 陈乾旺 教授）

2009.09 -- 2013.06      兰州大学                       物理科学与技术学院                          理学学士（Advisors: 王育华 教授 and 秦勇 教授）


研究方向        

[1] 多孔纳米酶/单原子纳米酶的设计、合成、酶促催化机理及在肿瘤成像与治疗中的应用研究

[2] 金属有机框架及其衍生物的设计、合成及在抗菌、肿瘤诊断与治疗中的应用研究

[3] 微生物及微生物合成纳米材料在肿瘤免疫治疗、催化中的应用研究


研究论文       

  1. Zhu, X., Bi, C., Cao, W., Li, S., Yuan, C., Xu, P., Wang, D.*, Chen, Q.*, Zhang, L.* A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment. J. Mater. Chem. B, 2024, 12, 8902-8910. Link (Journal of Materials Chemistry B Emerging Investigators 2024)

  2. Shi, H., Yang, Y.*, Meng, P., Yang, J., Zheng, W., Wang, P., Zhang, Y., Chen, X., Cheng, Z., Zong, C., Wang, D., Chen, Q. W.* Local Charge Transfer Unveils Antideactivation of Ru at High Potentials for the Alkaline Hydrogen Oxidation Reaction. J. Am. Chem. Soc., 2024, 10.1021/jacs.4c03622. Link

  3. Meng, P., Zheng, W., Shi, H., Yang, J., Wang, P., Zhang, Y., Chen, X., Zong, C., Wang, P., Cheng, Z., Yang, Y., Wang, D., Chen, Q. W.* Ultralow-Loading Ruthenium–Iridium Fuel Cell Catalysts Dispersed on Zn–N Species-Doped Carbon. Small, 2024, 2401404. Link

  4. Cheng, Z., Yang, Y., Zheng, F., Chen, S., Wang, P., Huang, H., Wang, C., Wang, D., Chen, Q. W.* Fast Kinetics of Hydrogen Oxidation Reaction on Single-Atom Ce-Alloyed Ru in Alkaline Electrolytes. ACS Catal., 2024, 14, 3845-3854. Link

  5. Zong, C., Zheng, W., Yang, Y., Wang, D., Wang, H.*, Chen, Q. W.* Ru/Ir nanojunctions supported on CNTs as active and ultrastable catalysts for CO preferential oxidation toward hydrogen purification. Chem. Eng. J., 2024, 14, 3845-3854. Link

  6. Duan, N., Hou, T., Zheng, W., Qu, Y., Wang, P., Yang, J., Yang, Y., Wang, D., Chen, J., Chen, Q. W.* Insight into the Structure of Mn-NiS2 during Urea Oxidation Using Combined In Situ X-ray Absorption Spectroscopy and Attenuated Total Reflectance Surface. ACS Catal., 2024, 14, 3845-3854. Link

  7. Cheng, Z., Yang, Y., Wang, P., Wang, P., Yang, J., Wang, D., Chen, Q. W.* Optimizing Hydrogen and Hydroxyl Adsorption over Ru/WO2.9 Metal/Metalloid Heterostructure Electrocatalysts for Highly Efficient and Stable Hydrogen Oxidation. Small, 2024, 14, 3845-3854. Link

  8. Wang, D., Liu, J., Wang, C., Zhang, W., Yang, G., Chen, Y., Zhang, X., Wu, Y., Gu, L., Chen, H., Yuan, W., Chen, X., Liu, G., Gao, B., Chen, Q. W., Zhao, Y. L.* Microbial Synthesis of Prussian Blue for Potentiating Checkpoint Blockade Immunotherapy. Nat. Commun., 2023, 14, 2943. Link

  9. Wang, D.*, Zhang, L., Wang, C., Cheng, Z., Zheng, W., Xu, P., Chen, Q. W.*, Zhao, Y. L.* Missing-Linker-Confined Single-Atomic Pt Nanozymes for Enzymatic Theranostics of Tumor. Angew. Chem. Int. Ed., 2023, 62, e202217995. Link

  10. Bindra, A., Wang, D.*, Zhao, Y. L.* Metal‐Organic Frameworks Meet Polymers: From Synthesis Strategies to Healthcare Applications. Adv. Mater., 2023, 35, 2300700. Link

  11. Wang, D., Wu, H., Phua, F., Lim, W., Yang, G., Lim, W., Gu, L., Qian, C., Wang, H., Guo, Z.*, Chen, H., Zhao, Y. L.* Self-Assembled Single-Atom Nanozyme for Enhanced Photodynamic Therapy Treatment of Tumor. Nat. Commun., 2020, 11, 357. Link (ESI 1% highly cited)

  12. Wang, D., Jana, D., Zhao, Y. L.* Metal-Organic Framework Derived Nanozymes in Biomedicine. Acc. Chem. Res., 2020, 53, 1389-1400. Link (ESI 1% highly cited)

  13. Wang, D., Wu, H., Lim, W., Phua, F., Xu, P., Chen, Q. W.*, Guo, Z.*, Zhao, Y. L.* A Mesoporous Nanoenzyme Derived from Metal-Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy. Adv. Mater., 2019, 31, 1901893. Link (ESI 1% highly cited)

  14. Wang, D., Zhao, Y. L.* Single-Atom Engineering of Metal-Organic Framework Toward Healthcare. Chem, 2021, 7, 2635-2671. Link

  15. Wang, D., He, W., Liu, J., Jana, D., Wu, Y., Zhang, X., Qian, C., Guo, Y., Chen, X., Bindra, A., Zhao, Y. L.* Missing-Linker-Assisted Artesunate Delivery by Metal-Organic Frameworks for Synergistic Cancer Treatment. Angew. Chem. Int. Ed., 2021, 60, 26254-26259. Link

  16. Wang, D., Wu, H., Wang, C., Gu, L., Chen, H., Jana, D., Wang, X., Xu, P., Guo, Z.*, Chen, Q. W.*, Zhao, Y. L.* Self-Assembly Single-Site Nanozyme for Tumor-Specific Amplified Cascade Enzymatic Therapy. Angew. Chem. Int. Ed., 2021, 60, 3001-3007. Link (ESI 1% highly cited)

  17. Wang, D., Wu, H., Yang, G., Qian, C., Gu, L., Wang, H., Zhou, W., Liu, J., Guo, Z.*, Chen, H., Jana, D., Zhao, Y. L.* Metal-Organic Framework Derived Multicomponent Nanoagent as a Reactive Oxygen Species Amplifier for Enhanced Photodynamic Therapy. ACS Nano, 2020, 14, 13500-13511. Link

  18. Jana, D.#, Wang, D.#, Bindra, A., Guo, Y.,  Liu, J., Zhao, Y. L.* Ultrasmall Alloy Nanozyme for Ultrasound- and Near-Infrared Light-Promoted Tumor Ablation. ACS Nano, 2021, 15, 7774-7782. Link (ESI 1% highly cited)

  19. Wang, C.#, Wang, D.#, Liu, S., Jiang, P., Lin, Z., Xu, P., Yang, K., Lu, J., Tong, H., Hu, L., Zhang, W., Chen, Q. W.* Engineering the Coordination Environment Enables Molybdenum Single-Atom Catalyst for Efficient Oxygen Reduction Reaction. J. Catal., 2020, 389, 150-156. Link

  20. Wang, D., Wu, H., Zhou, J., Xu, P., Wang, C., Shi, R., Wang, H.*, Guo, Z.*, Chen, Q. W.* In Situ One-Pot Synthesis of MOF-Polydopamine Hybrid Nanogels with Enhanced Photothermal Effect for Targeted Cancer Therapy. Adv. Sci., 2018, 5, 1800287. Link

  21. Wang, D., Shi, R., Zhou, J., Shi, S., Wu, H., Xu, P., Wang, H.*, Xia, G., Barnhart, T. E., Cai, W. B.*, Guo, Z.*, Chen, Q. W.* Photo-Enhanced Singlet Oxygen Generation of Prussian Blue-Based Nanocatalyst for Augmented Photodynamic Therapy. iScience. 2018, 9, 14-26. Link

  22. Qian, C., Feng, L., Teo, W., Liu, J., Zhou, W., Wang, D., Zhao, Y. L.* Imine and Imine-Derived Linkages in Two-Dimensional Covalent Organic Frameworks. Nat. Rev. Chem., 2022, 6, 881-898.  Link

  23. Wu, Y., Sun, L., Chen, X., Liu, J., Ouyang, J., Zhang, X., Guo, Y., Chen, Y., Yuan, W., Wang, D., He, T., Zeng, F., Chen, H. Z.*, Wu, S. Z.*, Zhao, Y. L.* Cucurbit[8]uril-Based Water-Dispersible Assemblies with Enhanced Pptoacoustic Performance for Multispectral Optoacoustic Imaging. Nat. Commun., 2023, 14, 3918. Link

  24. Zhao, Y., Song, S., Wang, D., Liu, H., Zhang, J., Li, Z. H.*, Wang, J. C.*, Ren, X. Z.*, Zhao, Y. L.* Nanozyme-Reinforced Hydrogel as A H2O2-Driven Oxygenerator for Enhancing Prosthetic Interface Osseointegration in Rheumatoid Arthritis Therapy. Nat. Commun., 2022, 13, 6758. Link

  25. Liu, J., You, F., He, B., Wu, Y., Wang, D., Zhou, W., Qian, C., Yang, G., Liu, G., Wang, H., Guo, Y., Gu, L., Feng, L. Li, S. Z., Zhao, Y. L.* Directing the Architecture of Surface-Clean Cu2O for CO Electroreduction. J. Am. Chem. Soc., 2022, 144, 12410-12420. Link

  26. Chen, Y., He, P., Jana, D., Wang, D., Wang, M., Yu, P., Zhu, W.*, Zhao, Y. L.* Glutathione-Depleting Organic Metal Adjuvants for Effective NIR-II Photothermal Immunotherapy. Adv. Mater., 2022, 34, 2201706. Link

  27. Yang, G., Wang, D., Phua, F., Bindra, A., Qian, C., Zhang, R., Cheng, L., Liu, G., Wu, H., Liu, Z.*, Zhao, Y. L.* Albumin-Based Therapeutics Capable of Glutathione Consumption and Hydrogen Peroxide Generation for Synergetic Chemodynamic and Chemotherapy of Cancer. ACS Nano, 2022, 16, 2319-2329. Link

  28. Gu, L., Ye, W., Liang, X., Lv, A., Ma, H., Singh, M., Jia, W., Shen, Z., Guo, Y., Gao, Y., Chen, H., Wang, D., Wu, Y., Liu, J., Wang, H., Zheng, Y.-X., An, Z. F.*, Huang, W.*, Zhao, Y. L.* Circularly Polarized Organic Room Temperature Phosphorescence from Amorphous Copolymers. J. Am. Chem. Soc., 2021, 143, 18527-18535. Link

  29. Zhang, X., Chen, X., Guo, Y., Gao, G., Wang, D., Wu, Y., Liu, J., Liang, G. L., Zhao, Y. L.*, Wu, F.-G.* Dual Gate-Controlled Therapeutics for Overcoming Bacterium-Induced Drug Resistance and Potentiating Cancer Immunotherapy. Angew. Chem. Int. Ed., 2021, 60, 14013-14021. Link

  30. Zhang, W., Liu, J., Li, X., Zheng, Y., Chen, L., Wang, D., Foda, M. F., Ma, Z., Zhao, Y. L.*, Han, H. Y.* Precise Chemodynamic Therapy of Cancer by Trifunctional Bacterium-Based Nanozymes. ACS Nano, 2021, 15, 19321-19333. Link

  31. Feng, L., Liu, B., Xie, R., Wang, D., Qian, C., Zhou, W., Liu, J., Jana, D., Yang, P. P.*, Zhao, Y. L.* An Ultrasmall SnFe2O4 Nanozyme with Endogenous Oxygen Generation and Glutathione Depletion for Synergistic Cancer Therapy. Adv. Funct. Mater., 2021, 31, 2006216. Link

  32. Qian, C., Zhou, W., Qiao, J., Wang, D., Li, X., Teo, W., Shi, X., Wu, H., Di, J., Wang, H., Liu, G., Gu, L., Liu, J., Feng, L., Liu, Y., Quek, S., Loh, K. P., Zhao, Y. L.* Linkage Engineering by Harnessing Supramolecular Interactions to Fabricate 2D Hydrazone-Linked Covalent Organic Framework Platforms toward Advanced Catalysis. J. Am. Chem. Soc., 2020, 142, 18138-18149. Link

  33. Wang, H., Qian, C., Liu, J., Zeng, Y., Wang, D., Zhou, W., Gu, L., Wu, H., Liu, G., Zhao, Y. L.* Integrating Suitable Linkage of Covalent Organic Frameworks into Covalently Bridged Inorganic/Organic Hybrids toward Efficient Photocatalysis. J. Am. Chem. Soc., 2020, 142, 4862-4871. Link

  34. Gu, L., Wu, H., Ma, H., Ye, W., Jia, W., Wang, H., Chen, H., Zhang, N., Wang, D., Qian, C., An, Z. F.*, Huang, W.*, Zhao, Y. L.* Color-Tunable Ultralong Organic Room Temperature Phosphorescence from A Multicomponent Copolymer. Nat. Commun., 2020, 11, 944. Link

  35. Wang, P., Yang, Y.*, Zheng, W., Cheng, Z., Wang, C., Chen, S., Wang, D., Yang, J., Shi, H., Meng, P., Wang, P., Tong, H., Chen, J., Chen, Q. W.* V–O Species-Doped Carbon Frameworks Loaded with Ru Nanoparticles as Highly Efficient and CO-Tolerant Catalysts for Alkaline Hydrogen Oxidation. J. Am. Chem. Soc., 2023, 145, 27867-27876. Link

  36. Zhao, Y., Wang, D., Qian, T., Zhang, J., Li, Z.*, Gong, Q.*, Ren, X.*, Zhao, Y. L.* Biomimetic Nanozyme-Decorated Hydrogels with H2O2-Activated Oxygenation for Modulating Immune Microenvironment in Diabetic Wound. ACS Nano, 2023, 17, 16854-16869. Link

  37. Tu, J., Tong, H., Wang, P., Wang, D., Yang, Y., Meng, X., Hu, L., Wang, H.*, Chen, Q. W.* Octahedral/Tetrahedral Vacancies in Fe3O4 as K-Storage Sites: A Case of Anti-Spinel Structure Material Serving as High-Performance Anodes for PIBs. Small, 2023, 19, 2301606. Link

  38. Yang, G., Bindra, A., Phua, F., Liu, J., Wu, H., Wang, D., Qian, C., Liu, G., Zhao, Y. L.* Light-Triggered Hypoxia-Responsive Nanoscale Metal-Organic Frameworks for Highly Efficient Antitumor Treatment. Adv. Optical Mater., 2023, 11, 2201043. Link



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