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教授
- 电子邮箱：6ed53d0fcaca0e678d0a20fd2166eb6f11841019f3444be109848698ed0b4d2ec3ede3fe13675a2a77a0f3c898e159ec8be1e40e09767ffae93eb725da4956728307dd3e1bcf63b44a0ba8ee6546860209a81268324231d9bff758a3ce63713165c0d0b75f95c56b72d4f4cf7aedbee991c53e0f7dafbbc0ad685edfd31ad7ec
- 联系方式：0551-63600520
- 学位：博士
- 2018年 国家海外高层次人才引进青年项目
- 2014年 美国LLS基金会Fellow Award
- 2012年 中科院院长优秀奖
访问量：
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[1]1. Chaoliang Li, Haohao Wang,Panrui Zhang,Jianbo Yang,Chao Ye,Xiaowei Wei, Yuchen Zhou, Zhentao Yang, Dan Cao,Kaiguang Zhang,Rongbin Zhou,Shu Zhu,and Wen Pan *VIPR1 acts as an enteric neural checkpoint that suppresses intestinal stem cell-driven epithelial regeneration and exacerbates colitis. Cell Stem Cell. 2026. Preview in "Neuronal VIP shapes intestinal stem cell activity and mucosal immunity" Cell Stem Cell..2026,
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[2]2. Hong Bao,Chen Yang, Panrui Zhang,Jiayang Zhang, Siyao Fang, Alin Yang,Zhentao Yang, Siwen Wang,Si Chen,Xuebiao Yao,Kaiguang Zhang, Shu Zhu, Dan Cao * and Wen Pan*. A gut-secreted histidine methyltransferase enforces cross-kingdom catalytic antifungal defense. Cell Host & MIcrobe. 2025. Preview in "METTL9 tests Candida's mettle by limiting metal acquisition". Cell Host & Microbe..2025,
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[3]3. Tao Tao, Lianbang Zhu, Deyun Shen, Jiayang Zhang , Panrui Zhang, Zhixi Gu , Dan Cao , Jun Xiao & Wen Pan A B cell-IgA-epithelial axis enhances antitumor immunity and improves outcome in HPV-associated penile squamous cell carcinoma.Nature Communications,2025,
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[4]4. Li C, Zhang P, Xie Y, Wang S, Guo M, Wei X, Zhang K, Cao D, Zhou R, Wang S, Song X#, Zhu S#, Pan W#. Enterococcus derived tyramine hijacks 2A-adrenergic receptor in intestinal stem cell to exacerbate colitis. Cell Host & Microbe. 2024 封面文章 (IF=20.1).
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[5]5. Cong J*, Liu P*, Ying W, Li C, Han Z, Yang J, Song X, Dai L, Sun L, Kasper D, Pan W#, Zhu S#. Bile acids modified by the microbiota suppress gut anti-tumor immune responses. Immunity. 2024 (IF=26.5) Preview in ‘Hostile bile limits anti-cancer immunity’, Immunity, 2024.
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[6]6. Zhu S#, Pan W#. Microbial metabolite steers intestinal stem cell fate under stress. Cell Stem Cell. 2024 (IF=20.9) Invited Comment..
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[7]7. Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z#, Li M#, Pan W#, Zhu S#. DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells. Nature Communications. 2024 (IF=16.6).
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[8]8. Wu Y, Zhang P, Shi T, Cao D#, Pan W# Deficiency of immunoglobulin IgSF6 enhances antibacterial effects by promoting endoplasmic reticulum stress and the inflammatory response in intestinal macrophages. Mucosal Immunology. 2024 (IF=8.7).
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[9]9. Dan Cao, Mengyue Lv, Chi Hu, Shukai Li, Siwen Wang, Chao Xu, Wen Pan#. METTL9-catalyzed histidine methylation of S100A9 suppresses the anti-Staphylococcus aureus activity of neutrophils. Protein & Cell. 2024 (IF=20.1).
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[10]10. A Wang, W Tao, J Tong, J Gao, J Wang, G Hou, C Qian, G Zhang, R Li, D Wang, X Ren, K Zhang, S Ding, R Flavell, HB Li, W Pan#, S Zhu#. m6A modifications regulate intestinal immunity and rotavirus infection. Elife. 2022 (IF=8.1).
