Zhangkaiming
- Special Professor
- Name (Pinyin):Zhangkaiming
- E-Mail:
- Degree:Dr
- Professional Title:Special Professor
- Alma Mater:Peking University
- Teacher College:Life Sciences
Contact Information
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- Paper Publications
- 1. Li S#, Hsieh KY#, Kuo CI, Su SC, Huang KF, Zhang K*, Chang CI*. Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv. 2021 Nov 12;7(46):eabj9537. doi: 10.1126/sciadv.abj9537. Epub 2021 Nov 10. PubMed PMID: 34757797..
- 2. Liu B#*, Li S#, Liu Y#, Chen H, Hu Z, Wang Z, Zhao Y, Zhang L, Ma B, Wang H, Matthews S, Wang Y*, Zhang K*. Bacteriophage Twort protein Gp168 is a β-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Res. 2021 Nov 8;49(19):11367-11378. doi: 10.1093/nar/gkab875. PubMed PMID: 34614154; PubMed Central PMCID: PMC8565349..
- 3. Cogan DP#, Zhang K#, Li X, Li S, Pintilie GD, Roh SH, Craik CS, Chiu W*, Khosla C*. Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science. 2021 Nov 5;374(6568):729-734. doi: 10.1126/science.abi8358. Epub 2021 Nov 4. PubMed PMID: 34735239..
- 4. Li S, Hsieh KY, Kuo CI, Lee SH, Pintilie GD, Zhang K*, Chang CI*. Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv. 2021 Oct 15;7(42):eabj7835. doi: 10.1126/sciadv.abj7835. Epub 2021 Oct 15. PubMed PMID: 34652947; PubMed Central PMCID: PMC8519571..
- 5. Li S, Hsieh KY, Su SC, Pintilie GD, Zhang K*, Chang CI*. Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease. J Biol Chem. 2021 Oct;297(4):101239. doi: 10.1016/j.jbc.2021.101239. Epub 2021 Sep 24. PubMed PMID: 34563541; PubMed Central PMCID: PMC8503904..
- 6.Zhang K#, Zheludev IN#, Hagey RJ#, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, D'Souza V, Glenn JS*, Chiu W*, Das R*. Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nat Struct Mol Biol. 2021 Sep;28(9):747-754. doi: 10.1038/s41594-021-00653-y. Epub 2021 Aug 23. PubMed PMID: 34426697. (Cover Story).
- 7. Su Z#*, Zhang K#, Kappel K#, Li S, Palo MZ, Pintilie GD, Rangan R, Luo B, Wei Y, Das R*, Chiu W*. Cryo-EM structures of full-length Tetrahymena ribozyme at 3.1 Å resolution. Nature. 2021 Aug;596(7873):603-607. doi: 10.1038/s41586-021-03803-w. Epub 2021 Aug 11. PubMed PMID: 34381213; PubMed Central PMCID: PMC8405103..
- 8. Li H#, Zhang K#, Binzel DW, Shlyakhtenko LS, Lyubchenko YL, Chiu W, Guo P*. RNA nanotechnology to build a dodecahedral genome of single-stranded RNA virus. RNA Biol. 2021 Apr 29;:1-11. doi: 10.1080/15476286.2021.1915620. [Epub ahead of print] PubMed PMID: 33845711..
- 9.Zhang K*, Pintilie GD, Li S, Schmid MF, Chiu W*. Resolving individual atoms of protein complex by cryo-electron microscopy. Cell Res. 2020 Dec;30(12):1136-1139. doi: 10.1038/s41422-020-00432-2. Epub 2020 Nov 2. PubMed PMID: 33139928; PubMed Central PMCID: PMC7605492..
- 10.Zhang K, Li S, Pintilie G, Chmielewski D, Schmid MF, Simmons G, Jin J, Chiu W*. A 3.4-Å cryo-electron microscopy structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles. QRB Discov. 2020 Nov 17;1:e11. doi: 10.1017/qrd.2020.16. PubMed PMID: 34192263; PubMed Central PMCID: PMC7737156..