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张凯铭
( 特任教授 )
的个人主页 http://faculty.ustc.edu.cn/ZhangKaiming/zh_CN/index.htm
特任教授
电子邮箱:
501a501f71cb4483aea0d096e9a58639cb36ad02a29ece2f54e2546f002b3605dfd43cbab29092326dadac38c649145b0d0fb6ec13fdce287dfa76680bb5574d919992b9679c2f45dbb03341fdc5327ea82b3062c06478d105507d82ac7d43c5e2d9671ddda3f75ad17e6e20ebf71d8aca30d93d78c3897acb3763a33adf088b
学位:
博士
毕业院校:
Peking University
论文成果
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[11]
11. Kappel K#, Zhang K#, Su Z#, Watkins AM, Kladwang W, Li S, Pintilie G, Topkar VV, Rangan R, Zheludev IN, Yesselman JD, Chiu W*, Das R*. Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures. Nat Methods. 2020 Jul;17(7):699-707. doi: 10.1038/s41592-020-0878-9. Epub 2020 Jul 2. PubMed PMID: 32616928; PubMed Central PMCID: PMC7386730..
[12]
12. Partin AC#, Zhang K#, Jeong BC, Herrell E, Li S, Chiu W, Nam Y*. Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA. Mol Cell. 2020 May 7;78(3):411-422.e4. doi: 10.1016/j.molcel.2020.02.016. Epub 2020 Mar 27. PubMed PMID: 32220646; PubMed Central PMCID: PMC7214211..
[13]
13.Zhang K#, Wang S#, Li S#, Zhu Y#, Pintilie GD, Mou TC, Schmid MF, Huang Z*, Chiu W*. Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7176-7182. doi: 10.1073/pnas.1922638117. Epub 2020 Mar 13. PubMed PMID: 32170016; PubMed Central PMCID: PMC7132274..
[14]
14. McClelland LJ#, Zhang K#, Mou TC#, Johnston J, Yates-Hansen C, Li S, Thomas CJ, Doukov TI, Triest S, Wohlkonig A, Tall GG, Steyaert J, Chiu W*, Sprang SR*. Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1. Nat Commun. 2020 Feb 26;11(1):1077. doi: 10.1038/s41467-020-14943-4. PubMed PMID: 32103024; PubMed Central PMCID: PMC7044438..
[15]
15. Guo S#, Vieweger M#, Zhang K#, Yin H, Wang H, Li X, Li S, Hu S, Sparreboom A, Evers BM, Dong Y, Chiu W, Guo P*. Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy. Nat Commun. 2020 Feb 20;11(1):972. doi: 10.1038/s41467-020-14780-5. PubMed PMID: 32080195; PubMed Central PMCID: PMC7033104.
[16]
16.Zhang K#, Li S#, Kappel K#, Pintilie G, Su Z, Mou TC, Schmid MF, Das R*, Chiu W*. Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 Å resolution. Nat Commun. 2019 Dec 3;10(1):5511. doi: 10.1038/s41467-019-13494-7. PubMed PMID: 31796736; PubMed Central PMCID: PMC6890682..
[17]
17.Zhang K#, Zhang H#, Li S#, Pintilie GD, Mou TC, Gao Y, Zhang Q, van den Bedem H, Schmid MF, Au SWN*, Chiu W*. Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6800-6805. doi: 10.1073/pnas.1821959116. Epub 2019 Mar 20. PubMed PMID: 30894496; PubMed Central PMCID: PMC6452728.
[18]
18. Guo M#, Zhang K#, Zhu Y, Pintilie GD, Guan X, Li S, Schmid MF, Ma Z, Chiu W*, Huang Z*. Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res. 2019 Apr;29(4):305-312. doi: 10.1038/s41422-019-0151-x. Epub 2019 Feb 27. PubMed PMID: 30814678; PubMed Central PMCID: PMC6461802..
[19]
19. Michalska K#, Zhang K#, March ZM#, Hatzos-Skintges C, Pintilie G, Bigelow L, Castellano LM, Miles LJ, Jackrel ME, Chuang E, Jedrzejczak R, Shorter J*, Chiu W*, Joachimiak A*. Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure. 2019 Mar 5;27(3):449-463.e7. doi: 10.1016/j.str.2018.11.001. Epub 2018 Dec 27. PubMed PMID: 30595457; PubMed Central PMCID: PMC6403000..
[20]
20. Jun H#, Shepherd TR#, Zhang K#, Bricker WP, Li S, Chiu W, Bathe M*. Automated Sequence Design of 3D Polyhedral Wireframe DNA Origami with Honeycomb Edges. ACS Nano. 2019 Feb 26;13(2):2083-2093. doi: 10.1021/acsnano.8b08671. Epub 2019 Jan 24. PubMed PMID: 30605605; PubMed Central PMCID: PMC6679942..
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