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张凯铭 ( 特任教授 )
的个人主页 http://faculty.ustc.edu.cn/ZhangKaiming/zh_CN/index.htm
特任教授

科学研究当前位置：中文主页 >> 科学研究

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1. Li S#, Hsieh KY#, Kuo CI, Su SC, Huang KF, Zhang K*, Chang CI*. Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv. 2021 Nov 12;7(46):eabj9537. doi: 10.1126/sciadv.abj9537. Epub 2021 Nov 10. PubMed PMID: 34757797..
2. Liu B#*, Li S#, Liu Y#, Chen H, Hu Z, Wang Z, Zhao Y, Zhang L, Ma B, Wang H, Matthews S, Wang Y*, Zhang K*. Bacteriophage Twort protein Gp168 is a β-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Res. 2021 Nov 8;49(19):11367-11378. doi: 10.1093/nar/gkab875. PubMed PMID: 34614154; PubMed Central PMCID: PMC8565349..
3. Cogan DP#, Zhang K#, Li X, Li S, Pintilie GD, Roh SH, Craik CS, Chiu W*, Khosla C*. Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science. 2021 Nov 5;374(6568):729-734. doi: 10.1126/science.abi8358. Epub 2021 Nov 4. PubMed PMID: 34735239..
4. Li S, Hsieh KY, Kuo CI, Lee SH, Pintilie GD, Zhang K*, Chang CI*. Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv. 2021 Oct 15;7(42):eabj7835. doi: 10.1126/sciadv.abj7835. Epub 2021 Oct 15. PubMed PMID: 34652947; PubMed Central PMCID: PMC8519571..
5. Li S, Hsieh KY, Su SC, Pintilie GD, Zhang K*, Chang CI*. Molecular basis for ATPase-powered substrate translocation by the Lon AAA+ protease. J Biol Chem. 2021 Oct;297(4):101239. doi: 10.1016/j.jbc.2021.101239. Epub 2021 Sep 24. PubMed PMID: 34563541; PubMed Central PMCID: PMC8503904..
6.Zhang K#, Zheludev IN#, Hagey RJ#, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, D'Souza V, Glenn JS*, Chiu W*, Das R*. Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nat Struct Mol Biol. 2021 Sep;28(9):747-754. doi: 10.1038/s41594-021-00653-y. Epub 2021 Aug 23. PubMed PMID: 34426697. (Cover Story).

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