个人信息Personal Information
特任研究员
博士生导师
硕士生导师
电子邮箱：
学历：研究生
办公地点：环资楼/苏州高等研究院
学位：博士
毕业院校：中国科学技术大学
课题组当前研究兴趣集中在创制新型聚合物功能材料，构建智能生物材料和程序化解聚高分子，应用于生物医药和可持续高分子材料。 聚焦于程序化可降解化学和精准高分子化学，融合大分子自组装、软物质纳米结构调控和生物正交化学策略，理解分子-聚集体-宏观材料的构效关系，为健康材料和绿色环境做贡献。
代表性论文：
1. Hou, M.#; Li, W.#; Cen, J.#; Pan, W.*; Deng, Z.*; Hu, J.*; Liu, S.* "Insight into Lysine Selection via Controlled Degradation of 2,4-Diaminobutyric Acid and Ornithine Polypeptides", Angew. Chem. Int. Ed. 2025, e202502629 (Selected as Hot Paper).
2. Deng, Z.; Gillies, E. R.* "Self-Immolative Polymers Derived from Renewable Resources via Thiol−Ene Chemistry", Angew. Chem. Int. Ed. 2025, 64, e202420054 (Included in Hot Topic: Click Chmistry).
3. Cen, J.#; Liu, W.#; Xu, J.#; Wang, X.; Zhang, J.; Zhang, J.; Deng, Z.*; Zhou, C.*; Hu, J.*; Liu, S.* "Single-Component High-Resolution Dual-Tone EUV Photoresists Based on Precision Self-Immolative Polymers", Angew. Chem. Int. Ed. 2025, 64, e202415588 (Selected as Hot Paper).
4. Deng, Z.; Liang, X.; Gillies, E. R.* "Click to Self-immolation: A “Click” Functionalization Strategy towards Triggerable Self-Immolative Homopolymers and Block Copolymers", Angew. Chem. Int. Ed. 2024, 63, e202317063 (Selected as Hot Paper).
5. Tan, J.#; Deng, Z.#; Song, C.; Xu, J.; Zhang, Y.; Yu, Y.; Hu, J*; Liu, S.* "Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification", J. Am. Chem. Soc. 2021, 143, 13738.
6. Yang, Q.#; Deng, Z.#; Wang, D.; He, J.; Zhang, D.; Tan, Y.; Peng, T.; Wang, X. Q.*; Tan, W.* "Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect", J. Am. Chem. Soc. 2020, 142, 2532.
7. Deng, Z.; Yuan, S.; Xu, X. R.; Liang, H.; Liu, S.* "Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates", Angew. Chem. Int. Ed. 2018, 57, 8896.
8. Deng, Z.; Qian, Y.; Yu, Y.; Liu, G.; Hu, J.; Zhang, G.; Liu, S.* "Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells", J. Am. Chem. Soc. 2016, 138, 10452 (ESI Highly Cited Papers).