我的研究主要聚焦于发展时间分辨固态核磁共振（Solid-state NMR）和同步辐射X射线散射（Synchrotron Radiation X-ray Scattering）技术，探究聚合物在外场作用下的结构与动力学响应。尤其关注聚合物薄膜体系，如高分子光学膜、电池极片和含能材料中高分子粘结剂。以下是我的具体研究方向：
研究方向一：时间分辨动力学与结构表征技术
1.1 固体核磁共振原位技术
基于低场时域NMR、单边NMR和高场固体核磁共振技术（NMR），我们开发了系列独特的原位NMR技术来跟踪高分子合成、加工和服役过程中分子动力学演变。近期代表性成果如下：
n Chen, X.; Li, C.; Wu, L.; Yan, S.; Qi, L.; Chen, J*.; Chen, W.* Low-Field NMR for Polymer Science. Giant 2025, 24, 100364. https://doi.org/10.1016/j.giant.2025.100364.
n Xiong, Y., Wu, Z., Wu, L., Li, C., & Chen, W.* Rheo-NMR: A versatile hyphenated technique for capturing molecular dynamics and structure under flow. Magnetic Resonance Letters, 2024，4(1), 100088. https://doi.org/10.1016/j.mrl.2023.10.002
n Xia, Z.; Wang, Y.; Gong, K.; Chen, W.* An in Situ Stretching Instrument Combined with Low Field Nuclear Magnetic Resonance (NMR): Rheo-Spin NMR. Rev. Sci. Instrum. 2022, 93 (3), 033905. https://doi.org/10.1063/5.0080767.
1.2 同步辐射X射线散射原位技术
针对包含长程有序结构的高分子体系，我们开发了多种同步辐射原位技术，实现在拉伸、剪切、压缩等工况下0.1 -1000 nm跨尺度结构在线检测。代表性成果如下：
n Chen, P.; Xia, Z.; Luo, Y.; Chen, W. *A Cryo -Bulge Apparatus for in Situ Weather Balloon Crystallization Capturing during Blowing by Synchrotron Radiation X-Ray Scattering. Rev. Sci. Instrum. 2022, 93 (5), 053901. https://doi.org/10.1063/5.0071132.
n Chen, P., Xia, Z., Luo, Y., & Chen, W.* A cryo -bulge apparatus for in situ weather balloon crystallization capturing during blowing by synchrotron radiation X-ray scattering. Review of Scientific Instruments, 2022，93(5), 053901. https://doi.org/10.1063/5.0071132
n Zhao, H., Li, L., Zhang, Q., Xia, Z., Yang, E., Wang, Y., Chen, W.*, Meng, L., Wang, D., & Li, L. Manipulation of Chain Entanglement and Crystal Networks of Biodegradable Poly(butylene adipate- co-butylene terephthalate) during Film Blowing through the Addition of a Chain Extender: An in Situ Synchrotron Radiation X-ray Scattering Study. Biomacromolecules, 2019，20(10), 3895–3907. https://doi.org/10.1021/acs.biomac.9b00975
n Zhao, J., Chen, P., Lin, Y., Chang, J., Lu, A., Chen, W.*, Meng, L., Wang, D., & Li, L.* Stretch-Induced Crystallization and Phase Transitions of Poly(dimethylsiloxane) at Low Temperatures: An in Situ Synchrotron Radiation Wide-Angle X-ray Scattering Study. Macromolecules, 2018，51(21), 8424–8434. https://doi.org/10.1021/acs.macromol.8b01872
研究方向二：高分子光学膜与光学透明胶
信息社会，显示无处不在。从日常的智能手机、平板电脑到高端的医疗成像设备和航空航天显示系统，显示面板已成为不可或缺的视觉交互界面。偏光片是薄膜晶体管液晶显示（TFT-LCD）和有机发光二极管（OLED）中的核心组件，由多层光学膜通过胶粘剂复合而成。其核心功能层为聚乙烯醇（PVA）偏光膜，以及膜间的胶粘剂如水性粘合剂、压敏胶。为此，我们围绕高分子光学胶膜开展了系列工作
2.1 高分子链结构精确表征与精准调控
序列决定结构，结构决定功能。围绕新型显示用高分子光学膜与光学透明胶，我们利用多维NMR和碳-13标定等技术实现对复杂高分子体系链结构解析，并结合机器学习实现对序列结构的精确表征。代表性成果如下：
n Chen, X.; Lv, C.; Li, Y.; Wu, Z.; Cao, R.; Fei, W.; Lv, J.; Chen, W.* Precise Characterization of the Sequence Distribution of Poly(Vinyl Butyral) (PVB) by 2D-NMR and Isotope Enrichment. Macromolecules 2023, 56 (8), 3036–3049. https://doi.org/10.1021/acs.macromol.3c00203.
n Tao, W.#, Yu, W.#, Zou, X., & Chen, W.* Machine learning assisted interpretation of 2D solid-state nuclear magnetic resonance spectra. Journal of Magnetic Resonance, 2023，353, 107492. https://doi.org/10.1016/j.jmr.2023.107492
2.2 高分子光学膜加工
显示面板包含多种高分子光学胶膜。其中偏光片中聚乙烯醇（PVA）偏光膜由PVA光学膜经过膨润、碘染、硼酸交联等多步加工制备而成，并通过水性粘合剂和光学透明胶等与其他光学膜复合形成光学模组。近期代表性工作如下：
n Liu, J.; Zhong, F.; Chen, W.*; Dong, X.*Molecular Compatibility and Optical Performance of PMMA/PTFS Hybrid Films. Macromolecules 2025. https://doi.org/10.1021/acs.macromol.5c00802.
n Li, Y.; Li, Y.; Cao, R.; Xie, J.; Chen, W.* Amplifying the Mechanical Resilience of Chemically Cross-Linked Poly(Vinyl Alcohol) Films with the Addition of Boric Acid. Macromolecules 2024, 57 (13), 6321–6332. https://doi.org/10.1021/acs.macromol.4c01098.
n Cheng, H.; Zhao, Y.; Wei, X.; Zhang, Q.; Yang, E.; Xiong, Y.; Zhu, J.; Wu, Z.; Chen, J.; Chen, W.* Supercooling and Solvent Depletion-Driven Poly(Vinyl Alcohol) Film Formation Mechanism as Elucidated by In Situ Synchrotron Radiation X-Ray Scattering. Macromolecules 2024, 57 (4), 1569–1580. https://doi.org/10.1021/acs.macromol.3c02640.
n Wu, Z.; Xiong, Y.; Li, C.; Cheng, H.; Li, Y.; Chen, W.* Exploring the Interphase Structure of Poly(Vinyl Alcohol) during Sol–Gel Transition Using Selective Probes with Varied Molecular Sizes. Macromolecules 2023, 56 (17), 7113–7124. https://doi.org/10.1021/acs.macromol.3c01089.
研究方向三：软物质力学微观机制
揭示软物质非线性力学微观机制是理解复杂流体和设计新型功能材料的重要前提。基于开发的核磁共振与同步辐射原位技术，我们得以建立宏观非线性力学与微观跨尺度结构和动力学耦合关系。代表性成果如下：
n Li, C.; Xia, Z.; Wu, L.; Xiong, Y.; Chen, W. *Strain-Dependent Evolution of the Rigid Amorphous Fraction of Low-Density Polyethylene under Deformation. Macromolecules 2025, 58 (5), 2320–2335. https://doi.org/10.1021/acs.macromol.4c02773.
n Wu, L.; Xiong, Y.; Li, C.; Chen, X.; Chen, W.* Strain-Induced Accelerated Chain Dynamics in Cross-Linked Natural Rubber under Active Deformation: An In Situ Nuclear Magnetic Resonance Study. Anal. Chem. 2025. https://doi.org/10.1021/acs.analchem.5c01483.
n Xiong, Y., Chen, X., Wu, L., Li, C., Lu, A., & Chen, W.* Molecular origin of stress softening in elastomer-based nanocomposites via in situ elongational nuclear magnetic resonance spectroscopy. Communications Materials, 2025，6(1), 187. https://doi.org/10.1038/s43246-025-00920-1
n Xiong, Y., Xia, Z., Lu, A., & Chen, W.* Time-Resolved Extensional Rheo-NMR Spectroscopy for Investigating Polymer Nanocomposites under Deformation. Analytical Chemistry, 2023，95(19), 7545–7551. https://doi.org/10.1021/acs.analchem.2c05788
n Feng, S.; Zhu, J.; Yu, W.; Guo, H.*; Chen, W.*; Lu, A.; Li, L. Strain-Rate-Dependent Phase Transition Mechanism in Polybutene-1 during Uniaxial Stretching: From Quasi-Static to Dynamic Loading Conditions. Macromolecules 2022, 55 (6), 2333–2344. https://doi.org/10.1021/acs.macromol.1c02561.
研究方向四：高分子结晶
近三分之二的高分子为半结晶性高分子。我们主要结合固体NMR与X射线散射技术来研究高分子早期成核、中间层链构象与取向信息等。代表性工作如下：
n Jin, X.; Zhang, Q.; Xiong, Y.; Wu, Z.; Cheng, H.; Chen, X.; Chen, W.* Molecular Mechanism of Surface Melting of Polyamide12 as Elucidated by Synchrotron Radiation X-Ray Scattering and 1H Spin Diffusion NMR. Macromolecules 2024, 57 (3), 1277–1290. https://doi.org/10.1021/acs.macromol.3c02574.
n Xiong, Y.-Q., Li, C.-L., Lu, A., Li, L.-B., & Chen, W.*Conformational Disorder Within the Crystalline Region of Silica-Filled Polydimethylsiloxane: A Solid-State NMR Study. Chinese Journal of Polymer Science, 2024，42(11), 1780–1792. https://doi.org/10.1007/s10118-024-3164-y
n Tang, X.#, Chen, W.#, & Li, L.* The Tough Journey of Polymer Crystallization: Battling with Chain Flexibility and Connectivity [Review]. Macromolecules, 2019,52(10), 3575–3591. https://doi.org/10.1021/acs.macromol.8b02725
n Chen, W., Wang, S., Zhang, W., Ke, Y., Hong, Y.-L., & Miyoshi, T.* Molecular Structural Basis for Stereocomplex Formation of Polylactide Enantiomers in Dilute Solution. ACS Macro Letters, 2015, 4(11), 1264–1267. https://doi.org/10.1021/acsmacrolett.5b00685