Scientific Research

Research Field

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Paper Publications

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• (8) Chen Y, Gallois-Montbrun S, Schneider B, Verron M, Morera S, Deville-Bonne D& Janin J. Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases. Journal Molecular Biology. 2003;332: 915-926..2021,
• (7) Chen Y, Solange Morera, Claudia Pasti, Angela Angusti, Nicola Solaroli, Michel Veron, Joel Janin, Stefano Manfredini & Dominique Deville-Bonne.　Adenosine phosphonoacetic acid is slowly metabolized by NDP Kinase. Medicinal Chimistry. 2005; 1(6): 529-536..2021,
• (6) Bao R, Chen Y*, Tang YJ, Janin J, Zhou CZ. Crystal structure of the yeast cytoplasmic thioredoxin Trx2.Proteins. 2007; 66(1): 246-249..2021,
• (4) Ma XX, Jiang YL, He YX, Bao R, Chen Y, Zhou CZ*. Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family. EMBO Reports. 2009; 10(12):1320-1326.2021,
• (3) Zhao MX, Jiang YL, He YX, Chen YF, Teng YB, Chen Y, Zhang CC* and Zhou CZ*. Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc Natl Acad Sci USA. 2010; 107(28) 12487-92..2021,
• (5) Bao R, Zhou CZ, Jiang C, Lin SX, Chi CW, Chen Y*. The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation. Journal of Biological Chemistry.2009; 284(39):26676-84..2021,

Patents

• chenyuxing ,zhoucongzhao,师伟伟,一种肺炎链球菌PiuA蛋白片段及其制备方法,201110149599.1,2012-12-05,2015-01-07.

Published Books

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Research Projects

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• 一组具有免疫原性的肺炎球菌表面蛋白的结构生物学研究,完成,
• 过氧化物酶体脂肪酸转运蛋白ABCD1/2/3的结构与功能研究,进行,
• 固有免疫通路关键蛋白和蛋白质机器的结构生物学研究,进行,
• 胆酸盐在肝脏循环中跨膜转运的结构基础,进行,
• 肺炎链球菌辅助分泌系统SecA2/SecY2的分子机制,进行,
• 真核耐药相关ABC膜转运蛋白的结构生物学,进行,