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DOI码：10.1021/acsami.1c20092

发表刊物：ACS Appl. Mater. Interfaces

关键字：2D metal−organic frameworks chemiluminescence functionalized nanomaterials porphyrin chemistry sensing small molecules

摘要：Two-dimensional (2D) porphyrin-based metal–organic frameworks (MOFs) hold great promise in a variety of areas with the merits of large lateral size and abundant functional groups. The chemiluminescent 2D MOF has rarely been reported. In this work, a chemiluminescence (CL) reagent and noble metal nanoparticle dual-functionalized 2D MOF (ABEI/AuNPs/CuTCPP) was developed through the surfactant-assisted and in situ synthetic growth method, exhibiting strong and stable CL property and outstanding peroxidase-mimicking activity. The special nanostructure of ABEI/AuNPs/CuTCPP endowed it with multi-catalytic routes in the CL reaction, which showed a unique pH-regulated and time-resolved CL kinetic curve. A CL mechanism with multi-catalytic centers has been proposed. AuNPs participated in the fast catalytic process and CuTCPP in the slow and strong catalytic reaction. Owing to the impressive structural features and intrinsic enzymatic tandem reaction from natural enzyme to artificial enzyme, a model biosensor was designed for the detection of small metabolic molecules. Employing choline as a model target, the proposed biosensor showed a highly sensitive response to choline in the linear range from 0.3 to 300 μM with a detection limit of 82.6 nM. Significantly, the strategy may be generalized to the monitoring of other biologically important compounds involved in the production of H2O2.

合写作者：王依莎,胡超

第一作者：王珏

论文类型：期刊论文

通讯作者：崔华

学科门类：理学

文献类型：J

卷号：14

期号：2

页面范围：3156–3164

是否译文：否

发表时间：2022-01-04

收录刊物：SCI

发布期刊链接：https://pubs.acs.org/doi/10.1021/acsami.1c20092