Scientific Research

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• Zhao MX,Jiang YL, He YX, Chen YF, Teng YB, Chen Y, Zhang CC*, Zhou CZ* Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate.Proc Natl Acad Sci U S A. 107(28):12487-92. 2010..2021,
• Zhao MX#,Jiang YL#, Xu BY, Chen Y, Zhang CC, Zhou CZ*. Crystal structure of the cyanobacterial signal transduction protein PII in complex with PipX.J Mol Biol. 402(3):552-9. 2010..2021,
• Jiang YL, Zhang JW, Yu WL, Cheng W, Zhang CC, Frolet C, Di Guilmi AM, Vernet T, Zhou CZ*, Chen Y*. Structural and enzymatic characterization of a Streptococcal ATP/diadenosine polyphosphate and phosphodiester hydrolase Spr1479/SapH.J Biol Chem. 286(41):35906-14. 2011..2021,
• Jiang YL, Yu WL, Zhang JW, Frolet C, Di Guilmi AM, Zhou CZ, Vernet T*, Chen Y*. Structural basis for the substrate specificity of a novel β-N-acetyl-hexosaminidase StrH protein from Streptococcus pneumoniae R6.J Biol Chem. 286(50):43004-12. 2011..2021,
• Hou WT, Li WZ, Chen Y,Jiang YL*, Zhou CZ*. Structures of yeast Apa2 reveal catalytic insights into a canonical Ap4A phosphorylase of the histidine triad superfamily.J Mol Biol. 425(15):2687-98. 2013..2021,
• Wang L,Jiang YL*, Zhang JR, Zhou CZ, Chen Y*. Structural and enzymatic characterization of the choline kinase LicA from Streptococcus pneumoniae.PLoS One. 10(3): e0120467. 2015..2021,

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Research Projects

• MapZ调控肺炎链球菌分裂环精确定位的分子机制,进行,
• 肺炎链球菌细胞分裂调控蛋白PcsB的结构酶学研究,进行,
• 肺炎链球菌荚膜多糖的合成和致病机理,进行,