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Scientific Research
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14) Wang C, Zhu Y, Bao H, Jiang Y, Xu C, Wu J*, Shi Y*.A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1., Nucleic Acids Res. 2015 Dec 15. pii: gkv1382. [Epub ahead of print].2021,
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13) Liu Z., Li F., Zhang B., Li S., Wu J.,* and Shi* Y., Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex. Journal of Biological Chemistry (2015) 290:6630-6638..2021,
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11)Liu Z, Li F, Ruan K, Zhang J, Mei Y, Wu J*, Shi Y*, Structural and functional insights into the human Börjeson-Forssman-Lehmann syndrome-associated protein PHF6.J Biol Chem. 2014, 289(14):10069-83.2021,
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10)Wang J, Qin S, Li F, Li S, Zhang W, Peng J, Zhang Z, Gong Q, Wu J*, Shi Y*. Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosomes binding. Cell Res. 2014.24, 890-3 2014.38..2021,
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12) Wang L., Wang W, Li F., Zhang J, Wu J., Gong*Q. and Shi*Y. ,Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq. Nucleic Acids Research (2015) 43(4):2400-2411..2021,
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RNA蛋白质亚细胞器的相分离和相变对神经发育与功能的影响,进行,
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衰老的遗传与表观遗传调控的分子机理及与退行性病变的发生发展机制,进行,
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衰老的遗传与表观遗传调控,进行,
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应激颗粒核心组分G3BP1,TTP对应激颗粒组装去组装的调控机制研究,进行,
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细胞黏性连接及紧密连接处Nectin-AF-6系统及claudin-ZOs系统蛋白质相互作用的三维结构基础,完成,