代表性论文:
1. Sun, D.#, Li, X.#, Yuan, Q.#, Wang, Y.#, Shi, P., Zhang, H., Wang, T., Sun, W., Ling, S., Liu, Y., Lai, J., Xie, W., Yin, W.*, Liu, L.*, Xu, H.E.*, Tian, C.* Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator. Cell Res. (2025) 35(4): 284-295
2. Cao, X. #, Chen, H. #, Wang, X. #, Yang, X., Wang, T., Zhou, L., Shi, C., Liu, S., Tian, C.*, and Sun, D.*. De novo discovery of unnatural and potent conotoxin-like bicyclic peptides through a phage-encoded library. Sci China Chem. (2025) 68.
3. Cao, X. #, Liu, T. #, Wang, T. #, Wang, X., Xu, Z., Zhou, L., Tian, C.*, and Sun, D.* De Novo Screening and Mirror Image Isomerization of Linear Peptides Targeting alpha7 Nicotinic Acetylcholine Receptor. ACS Chem Biol (2024) 19, 592-598.
4. Zuo, C.#, Ding, R.,# Wu, X.#, Wang, Y., Chu, G.C., Liang, L.J., Ai, H., Tong, Z.B., Mao, J., Zheng, Q., Wang, T., Li, Z., Liu, L.*, Sun, D.* Thioester-Assisted Sortase-A-Mediated Ligation. Angew Chem Int Ed (2022) 61: e202201887.
5. Wang, L.#, Li, H. #, Wang, X., Yang, X., Tian, C., Sun, D.*, Liu, L., Li, J.* (2023). Modification of low-energy eurfaces using bicyclic peptides discovered by phage display. J Am Chem Soc (2023) 145, 17613-17620.
6. Wang, T.#, Cao, X.#, Zheng, Y., Chen, C., Zhou, L., Sun, D.*, Fang, G.*, Tian, C.* Total stepwise solid-phase synthesis of peptide-oligonucleotide conjugates using side-chain Boc/tBu protecting groups. Chem Commun (Camb) (2023) 59, 5839-5842.
7. Ling, S.#, Shi, P.#, Liu, S.#, Meng, X.#, Zhou, Y., Sun, W., Chang, S., Zhang, X., Zhang, L., Shi, C., Sun, D.*, Liu, L.*, Tian, C.* Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan. Cell Res (2021) 31, 383-394.
8. Zhao, Y.#, Liu, S.#, Zhou, Y.#, Zhang, M., Chen, H., Eric Xu, H., Sun, D.*, Liu, L.*, and Tian, C.* Structural basis of human alpha7 nicotinic acetylcholine receptor activation. Cell Res (2021) 31, 713-716.
9. Li, Y.#, Heng, J.#, Sun, D.*, Zhang, B., Zhang, X., Zheng, Y., Shi, W., Wang, T., Li, J., Sun, X., Liu, X., Zheng, J.*, Brain Kobilka, Liu, L.* Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor β2-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus. J Am Chem Soc (2021) 143, 17566-17576.
10. Li, S.#, Yang, F.#, Sun, D.#*, Zhang, Y.#, Zhang, M., Liu, S., Zhou, P., Shi, C., Zhang, L.#, and Tian, C.# Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis. Cell Res. (2020) 30:1049-1052.
11. Sun, D.#, Liu, S.#, Li, S.#, Zhang, M.#, Yang, F., Wen, M., Shi, P., Wang, T., Pan, M., Chang, S., Zhang, X., Zhang, L.*, Tian, C.*, Liu, L.* Structural Insights into Human Acid-sensing Ion Channel 1a Inhibition by Snake Toxin Mambalgin1. Elife (2020) 9.


English
登录
