1. Methodology & Tool Development: Developing and integrating in situ cryo-ET, super-resolution fluorescence microscopy, and AI-based computation. 2. Synaptic Biology: Resolving the molecular and cellular mechanisms of synaptic transmission and plasticity. 3. Structural Cell Biology: Deciphering macromolecular structures in situ and building molecular-scale digital models of intact cells.
1. Methodology & Tool Development: Developing and integrating in situ cryo-ET, super-resolution fluorescence microscopy, and AI-based computation.
2. Synaptic Biology: Resolving the molecular and cellular mechanisms of synaptic transmission and plasticity.
3. Structural Cell Biology: Deciphering macromolecular structures in situ and building molecular-scale digital models of intact cells.


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