wangyi
- Special Researcher
- Name (Pinyin):wangyi
- E-Mail:
- Degree:Dr
- Professional Title:Special Researcher
- Teacher College:Life Sciences
Contact Information
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- Paper Publications
- 1) Jing Jin#, Peidong Yan#, Dongyao Wang#*, Lin Bai#, Hao Liang, Xiaoyu Zhu, Huaiping Zhu, Chen Ding*, Haiming Wei*, Yi Wang*. Targeting lactylation reinforces NK cell cytotoxicity within the tumor microenvironment. Nature Immunology, June 10, 2025. https://doi.org/10.1038/s41590-025-02178-8.
- 2) Yunjia Li#, Lin Bai#, Hao Liang#, Peidong Yan#, Hao Chen#, Zhuoxian Cao#, Yiqing Shen, Zhongyv Wang, Mei Huang, Bin He, Quan Hao, Yide Mei, Haiming Wei, Chen Ding*, Jing Jin*, Yi Wang*. A BPTF-specific PROTAC degrader enhances NK cell-based cancer immunotherapy. Molecular Therapy, 2025; 33(4):1566-1583..
- 3) Yunjia Li#, Yiqing Shen#, Hao Chen#, Lin Xue, Mei Huang, Haiming Wei, Jing Jin*, Yi Wang*. A heparanase-specific LYTAC degrader reinforces natural killer cell cytotoxicity within the tumor microenvironment. Cell Reports Physical Science, 2024, 5 (12)..
- 4) Jing Jin#,* Lin Bai#, Dongyao Wang#, Wei Ding, Zhuoxian Cao, Peidong Yan, Yunjia Li, Lulu Xi, Yuxing Wang, Xiaohu Zheng, Haiming Wei, Chen Ding*, Yi Wang*. SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth. EMBO Reports, 2023, 24 (5), e56052..
- 5) Xinyuan Xu#, Qian Zhang#, Xufeng Wang#, Jing Jin#, Chengwei Wu#, Li Feng#, Xiuyan Yang, Mingzhu Zhao, Yingyi Chen, Shaoyong Lu, Zhen Zheng, Xiaobing Lan, Yi Wang*, Yan Zheng*, Xuefeng Lu*, Qiufen Zhang* Jian Zhang*. Discovery of a potent and highly selective inhibitor of SIRT6 against pancreatic cancer metastasis in vivo, Acta Pharmaceutica Sinica B, 2024; 14(3): 1302-1316..
- 6) Jing Jin#, Bin He#, Xiaoyu Zhang, Hening Lin*, Yi Wang*. SIRT2 reverses 4-oxononanoyl lysine modification on histones. J. Am. Chem. Soc., 2016, 138 (38), pp 12304–12307..
- 7) Hong Jiang#, Saba Khan#, Yi Wang#, Guillaume Charron, Bin He, Carlos Sebastian, Jin tang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao* & Hening Lin*. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 2013, 496, (110–113)..
- 8) Yi Wang#, Jing Jin#, Matthew Wai Heng Chung#, Ling Feng, Hongyan Sun, Quan Hao*. Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation. Proc Natl Acad Sci U S A. 2018, Feb 20. pii: 201717664..
- 9) Yi Wang, Yi Man Eva Fung, Weizhe Zhang, Bin He, Matthew Wai Heng Chung, Jing Jin, Jing Hu, Hening Lin, Quan Hao*. De-acylation Mechanism by SIRT2 Revealed in the 1’-SH-2’-O-MyristoylIntermediate Structure. Cell Chemical Biology, 2017. 16; 24(3): 339-345..
- 10) Xiucong Bao#, Yi Wang#, Xin Li#, Xiao-Meng Li#, Zheng Liu, Tangpo Yang, Chi Fat Wong, Jiangwen Zhang, Quan Hao*, Xiang David Li*. Identification of ‘erasers, SIRT3’ for lysine crotonylated histone marks using a chemical proteomics approach. elife.2014; 3: e02999..