Supervariate Gel Transforms into Various Biominerals in Salt Solutions
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影响因子：18.5
DOI码：10.1002/adfm.202504321
发表刊物：Advanced Functional Materials
摘要：It is disclosed that calcium-based biominerals, particularly hydroxyapatite (as in vertebrate bones and teeth), calcium carbonate (as in plankton and corals), and calcium pyrophosphate (as the cause for pseudogout), can be mineralized from the same precursor—“supervariate” gel, a stable and non-toxic amorphous gel easily prepared by mixing common water-soluble inorganic salt. When dispersed in a Na2CO3 or K2HPO4 solution, this multi-ionic, “supervariate” gel can selectively form the biomineral calcite (CaCO3) or hydroxyapatite, respectively. More remarkable reactions happen when the gel is dispersed in a CaCl2 solution under ambient conditions: dihydrate calcium pyrophosphate (Ca2P2O7·2H2O, CPP) is produced in the morphologically intact gel matrix. The resulting gel further transforms into hydroxyapatite upon drying at room temperature. Because of the ubiquity of pyrophosphate in organisms, such mild formation of calcium pyrophosphate dihydrate (contrasting the high temperatures needed in other non-enzymatic procedures, e.g., as in condensing phosphoric acid), and its transformation into hydroxyapatite, sheds light on 1) the role of pyrophosphate in life's origin; 2) key biomineralization mechanisms in physiological processes. This “supervariate” gel is also applied for dental repair and osteogenesis.
第一作者：Xinxue Tang
合写作者：Chong Wang,Yuk-Tong Cheng,Junda Shen,Yunchen Long,Hongkun Li,Jie Yan,Yang Ren,Xiao Ma,Yufeng Huang
论文类型：期刊论文
通讯作者：Zhengtao Xu,Jian Lu,Yang Yang Li
页面范围：2504321
是否译文：否
发表时间：2025-04-17
收录刊物：SCI