肖石燕  (特任教授)

博士生导师 硕士生导师

电子邮箱:

学历:研究生

学位:博士

毕业院校:中国科学技术大学

学科:化学

论文发表列表

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56. G. Chen, X. Li, Y. Huang, C. Zheng, H. Fang, Q. Zhang, K. Liu, K. Wu, Q. Zhu, C. Guo, H. Zhu, R. Dai, Y. He, Q. Zhu, W. Zhou, Y. Yang, Z. Li, K. Qu*, B. Li*, S. Xiao*, S. Tian, B. Xing, X. Chen, A. Z. Wang, Y. Xiong, Yuanzeng Min*; Platinonitrene-based radiosensitizer boosts radiotherapy and abscopal effect, Nat. Biomed. Eng, 2025, Accepted.

55. Z. Li, C. Li, S. Xiao*, H. Liang; Efficient and Precise Integration of Large DNA Sequences Using Precise Interstrand Cross-Linking of Long ssDNA and sgRNA; ACS Synth. Biol 2025, 14(5), 14511463.

54. S. Zhou#, P. Lyu#, Y. Huang, X. Man*,  S. Xiao*; Nonmonotonous Translocation Dynamics of Highly Deformable Particles across Channels; ACS Nano 2025, 19, 10807–10815.

53. Y Liang#, Y Zhang#, Y Huang#, C Xu#, J Chen, X Zhang, B Huang, Z Gan, X Dong, S Huang, C Li, S Jia, P Zhang, Y Yuan, H Zhang, Y Wang, B Yuan, Y Bao*, S Xiao*, M Xiong*; Helicity-directed recognition of bacterial phospholipid via radially amphiphilic antimicrobial peptides; Sci. Adv. 2024, 10, eadn9435.

52. Z Li, Y Ma, C Li, S Xiao*, H Liang; Photo‐Cross‐linked DNA Structures Greatly Improves Their Serum Nuclease Resistances and Gene Knock‐In Efficiencies. Small Methods. 2024, 2401346. (邀稿,Wiley MaterialsViews 官方报道: https://mp.weixin.qq.com/s/ti3xtnDOZeeRvzvHPOqdOw)

51. C Li, S Xiao*, H Liang*; The effects of fluorescent pair on the kinetics of DNA strand displacement reaction; Chinese J. Chem. Phys. 2024, 37 (5), 679-684.

50. Y Zhang, S Xiao*, H Liang*; Avoiding Kinetic Trapping in the Self-Assembly of DNA-Functionalized Gold Nanoparticles by Using an Enthalpy-Mediated Strategy; Macromolecules 2023, 56 (9), 3454-3463.

49. X Yang, W Shi, Z Chen, M Du, S Xiao*, S Qu*, C Li*; Light-Fueled Nonequilibrium and Adaptable Hydrogels for Highly Tunable Autonomous Self-Oscillating Functions; Adv. Funct. Mater. 2023, 33 (24), 2214394.

48. Y Du, Y Zhang, J. Jin*, S. Xiao*, H Liang, W Jiang*; Topology-Directed Self-Locking of Colloidal Suprastructures; Macromolecules 2023, 56 (9), 2781–2789.

47. S Xiao*#, C. Li#, H Liang*; DNA: structure, strand displacement and reaction network; SCIENTIA SINICA Chimica 2023, doi: 10.1360/SSC-2023-0006. (邀稿)

46.T Chen, Y Zhang*, S Xiao, D Yao, W Jiang*, H Liang*; Catalytic assembly of symmetric diblock copolymers in a thin film: A dissipative particle dynamics simulation; Phys. Chem. Chem. Phys. 2023, 25 (14), 9779-9784.

45. M. Liu#, L. Huang#, W. Zhang#, X. Wang, Y. Geng, Y. Zhang, L. Wang, W. Zhang, Y. Zhang, S. Xiao*, Y. Bao*, M. Xiong*, and J. Wang*; A transistor-like pH-sensitive nanodetergent for selective cancer therapy; Nat. Nanotechnol. 2022, 17 (5), 541-551.

44. Z Chen, S Zheng, Z Shen, J Cheng, S Xiao*, G Zhang, S Liu*, J Hu*; Oxygen-Tolerant Photoredox Catalysis Triggers Nitric Oxide Release for Antibacterial Applications; Angew. Chem. Int. Ed. 2022, 61 (30), e202204526.

43. C. Li, Z. Li, W. Han, X. Yin, X. Liu, S. Xiao*, and H. Liang*; How the Fluorescent Labels Affect the Kinetics of Toehold-Mediated DNA Strand Displacement Reaction?; Chem. Commun. 2022, 58, 5849-5852.

42. C Li, S Xiao*, H. Liang*; Regulation of Gene Expression via Toehold Switch in E. coli; J. Funct. Polym. 2023, 36(3), 302-309.

41. H Zhang, S Shan, Y Huang, S Xiao, D Chen, G Zou*; Regulable chiral amplification effects in copoly (phenylacetylene) s and bidirectional manipulation for helix preferences; J. Mater. Chem. C 2022, 10 (38), 14265-14272.

40. Z. Shen, S. Zheng, S. Xiao*, R. Shen, S. Liu*, and J. Hu*; Red-Light-Mediated Photoredox Catalysis Enables Self-Reporting Nitric Oxide Release for Efficient Antibacterial Treatment; Angew. Chem. Int. Ed. 2021, 60 (37), 20452-20460.

39. T. Chen, Y. Zhang, X. Li, C. Li, T. Lu, S. Xiao*, and H. Liang*; Curvature-Mediated Pair Interactions of Soft Nanoparticles Adhered to a Cell Membrane; J. Chem. Theory Comput. 2021, 17 (12), 7850-7861.

38. J. Li, Z. Ge*, K. Toh, X. Liu, A. Dirisala, W. Ke, P. Wen, H. Zhou, Z. Wang, S. Xiao, J. F. R. Van Guyse, T. A. Tockary, J. Xie, D. Gonzalez-Carter, H. Kinoh, S. Uchida, Y. Anraku, and K. Kataoka*; Enzymatically Transformable Polymersome-Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer; Adv. Mater. 2021, 33 (49), 2105254.

37. Y. Guo, D. Yao*, B. Zheng, X. Sun, X. Zhou, B. Wei, S. Xiao, M. He, C. Li, and H. Liang*; pH-Controlled Detachable DNA Circuitry and Its Application in Resettable Self-Assembly of Spherical Nucleic Acids, ACS Nano 2020, 14, 8317–8327.

36. B. Wei, X. Sun*, D. Yao, C. Li, S. Xiao, Y. Guo, and H. Liang*; Homogeneous DNA-only keypad locks enable one-pot assay of multi-inputs,Chem. Commun. 2020, 56, 7427-7430.

35. X Zhou#, D. Yao#, W. Hua, N. Huang, X. Chen, L. Li*, M. He, Y. Zhang, Y Guo, S. Xiao*, F., Bian*, and H. Liang*; Programming colloidal bonding using DNA strand-displacement circuitry, PNAS 2020, 117 (11), 5617-5623.

34. S Xiao, D Sharpe, D Chakraborty, D Wales*; Energy Landscapes and Hybridization Pathways for DNA Hexamer Duplexes; J. Phys. Chem. Lett. 2019, 10 (21), 6771-6779.

33. S Xiao, H Liang*, D Wales*; The Contribution of Backbone Electrostatic Repulsion to DNA Mechanical Properties is Length-Scale-Dependent; J. Phys. Chem. Lett. 2019, 10, 4829-4835.

32. C He#, M Wang#, X Sun, Y Zhu, X Zhou, S Xiao*, Q Zhang, F Liu, Y Yu, H Liang, G Zou*; Integrating PDA microtube waveguide system with heterogeneous CHA amplification strategy towards superior sensitive detection of miRNA; Biosens. Bioelectron. 2019, 129, 50-57.

31. T Zuo, C Ma, G Jiao, Z Han, S Xiao, H Liang, L Hong, D Bowron*, A Soper, C C. Han, H Cheng*; Water/Cosolvent Attraction Induced Phase Separation: A Molecular Picture of Cononsolvency; Macromolecules 2019, 52 (2), 457-464.

30. H Tang, Z Gu, H Ding, Z. Li, S Xiao, W. Wu, X Jiang*; Nanoscale Crystalline Sheets and Vesicles Assembled from Non-Planar Cyclic pi-Conjugated Molecules; Research 2019, 1953926.

29. B Wei, D Yao*, B Zheng, X Zhou, Y Guo, X Li, C Li, S Xiao, H Liang*; A Facile Strategy for Visible Disassembly of Spherical Nucleic Acids Programmed by Catalytic DNA Circuit; ACS Appl. Mater. Interfaces 2019, 11 (22), 19724-19733.

28. X Li, X Sun, J Zhou, D Yao, S Xiao, X Zhou, B Wei, C Li, H Liang*; Enzyme-assisted waste-to-reactant transformation to engineer renewable DNA circuits; Chem. Commun.  2019, 55 (77), 11615-11618.

27. X Sun, B Wei, Y Guo, S Xiao*, X Li, D Yao, X Yin, S Liu, H Liang*; A Scalable “Junction Substrate” to Engineer Robust DNA Circuits; J. Am. Chem. Soc. 2018, 140 (31), 9979–9985. (被选为当期JACS封面文章)

26. L Chen, X Li, Y Zhang, T Chen, S Xiao* and HJ Liang*; Morphological and mechanical determinants of cellular uptake of deformable nanoparticles; Nanoscale 2018, 10, 11969-11979.

25. Y Zhang, T Chen, Z Pan, X Sun, X Yin, M He, S Xiao*, H Liang; Theoretical Insights into the Interactions between Star-shaped Antimicrobial Polypeptides and Bacterial Membrane; Langmuir 2018, 34 (44), 13438-13448.

24. X Zhou#, D Yao#, M He, S Xiao*, H Liang*; Optimizing the Toehold Strategy of On-Chip Nucleic Acid Hybridization Probe for the Discrimination of Single Nucleotide Polymorphism; Langmuir 2018, 34 (49), 14811-14816.

23. Y Guo#, B Wei#, X Sun, D Yao, X Zhou, S Xiao*, H Liang*; DNA and DNA computation based on toehold-mediated strand displacement reactions; Int. J. Mod. Phys. B 2018, 32, 1840014.

22. X Zhou#, H Li#, M He, X Yin, D Yao, S Xiao, H Liang*; Photoresponsive spherical nucleic acid: spatiotemporal control of the assembly circuit and intracellular microRNA release; Chem. Commun. 2018, 54, 106-109.

21. J Li#, S Xiao#, Y Xu, S Zuo, Z Zha, W Ke, C He*, Z-S Ge*; Smart Asymmetric Vesicles with Triggered Availability of Inner Cell-Penetrating Shells for Specific Intracellular Drug Delivery; ACS Appl. Mater. Interfaces 2017, 9 (21), 17727–17735. (# 共同一作)

20. D Yao,  S Xiao*,  X Zhou,  H Li,  B Wang,  B Wei and H Liang*; Stacking Modular DNA Circuitry in Cascading Self-Assembly of Spherical Nucleic Acids; J. Mater. Chem. B 2017, 5, 6256–6265. (“Hot Paper” theme of J. Mater. Chem. B)

19. Y Guo, B Wei, S Xiao, D Yao, H Li, H Xu, T Song, X Li, H Liang*; Recent advances in molecular machines based on toehold-mediated strand displacement reaction; Quantitative Biology 2017, 5 (1), 25–41.

18. L Chen, S Xiao*, H Zhu, L Wang and H Liang; Shape-dependent internalization kinetics of nanoparticles by membranes; Soft Matter 2016, 12 (9), 2632-2641.

17. D Yao, H Li, Y Guo, X Zhou, S Xiao* and H Liang*; A pH-responsive DNA nanomachine controlled catalytic assembly of gold nanoparticles; Chem. Commun. 2016, 52, 7556-7559.

16. S Xiao and H Liang*; DNA and DNA computation based on toehold-mediated strand displacement reactions; Acta Phys. Sin. 2016, 65 (17), 178106.

15. D Yao, T Song, X Sun, S Xiao*, F Huang and H Liang*; Integrating DNA Strand Displacement Circuitry with Self-Assembly of Spherical Nucleic Acids; J. Am. Chem. Soc. 2015, 137 (44), 14107-14113.

14. D Yao, B Wang, S Xiao*, T Song, F Huang and H Liang*; What Controls the “Off/On Switch” in the Toehold-Mediated Strand Displacement Reaction on DNA Conjugated Gold Nanoparticles? Langmuir 2015, 31 (25), 7055–7061.

13. D Yao, T Song, B Zheng*, S Xiao, F Huang, H Liang*; The combination of gold nanorods and nanoparticles with DNA nanodevices for logic gates construction; Nanotechnology 2015, 26 (42), 425601.

12. H Li,   S Xiao,   D Yao,   M H W Lam* and  H Liang* ; A Smart DNA-Gold Nanoparticle Probe for Detecting Single-base Changes on the Platform of Quartz Crystal Microbalance; Chem. Commun. 2015, 51, 4670-4673.

11. T Song, S Xiao*, F Huang, M Hu, and H Liang*; An efficient DNA-fueled molecular machine for the discrimination of single-base changes; Adv. Mater. 2014, 26 (35), 6181-6185.

10. S Xiao, H Zhu, L Wang, L Chen and H Liang*; Enhancing the efficiency of lithium intercalation in carbon nanotube bundles using surface functional groups; Phys. Chem. Chem. Phys. 2014, 16, 16003-16012.

9. S Xiao, H Zhu, L Wang, and H Liang*; DNA conformational flexibility study using phosphate backbone neutralization model; Soft Matter 2014, 10, 1045-1055.

8. S Xiao, M. L. Klein, D. N. Lebard, B. G. Levine, H Liang, M. Alfonso-Prieto*; Magnesium-dependent RNA Binding to the PA Endonuclease Domain of the Avian Influenza Polymerase; J. Phys. Chem. B 2014, 118, 873-889.

7. F Huang, X Zhou, D Yao, S Xiao and H Liang*; DNA Polymer Brush Patterning through Photocontrollable Surface‐Initiated DNA Hybridization Chain Reaction; Small 2015, 11 (43), 5800-5806.

6. H Zhu, S Xiao, L Wang, and H Liang*; Asymmetrical Cation Movements through G-quadruplexes DNA; J. Chem. Phys. (Communication) 2014, 141, 041103.

5. H Xu, W Deng, F Huang*, S Xiao, G Liu, H Liang*; Enhanced DNA toehold exchange reaction on a chip surface to discriminate single-base changes; Chem. Commun. 2014, 50 (91), 14171-14174.

4. L Wang, N Li, S Xiao, and H Liang*; Thermodynamic and conformational insights into the phase transition of a single flexible homopolymer chain using replica exchange Monte Carlo method; J. Mol. Modeling 2014, 20, 1-10.

3. H Zhu, S Xiao and H Liang*; Structural Dynamics of Human Telomeric G-quadruplex Loops Studied by Molecular Dynamics Simulations; PLoS ONE 2013, 8 (8), e71380.

2. S Xiao and H Liang*; The conformational flexibility of nucleic acid bases paired in gas phase: A Car-Parrinello molecular dynamics study; J. Chem. Phys. 2012, 136, 205102. (selected for the June 1, 2012 issue of Virtual Journal of Biological Physics Research.)

1. S Xiao, L Wang, Y Liu, X Lin and H Liang*; Theoretical investigation of the proton transfer mechanism in guanine-cytosine and adenine-thymine base pairs; J. Chem. Phys. 2012, 137, 195101.


* Google scholar citations: http://scholar.google.com/citations?user=Jo0QvogAAAAJ