• 其他栏目

    曹洋

    • 特任教授
    • 教师英文名称:Yang Cao
    • 电子邮箱:
    • 办公地点:科大西区医学楼434
    • 联系方式:yangcao208@ustc.edu.cn
    • 学位:博士

    访问量:

    开通时间:..

    最后更新时间:..

    教学信息

    当前位置: 中文主页 >> 教学信息
    1. Cao Y, Wang      Y-C, Zhou Z, Pan C, Jiang L, Zhou Z, Meng Y, Charugundla S, Li T, Allayee      H, Seldin MM, and Lusis AJ. Liver-heart cross-talk mediated by coagulation      factor XI protects against heart failure. Science. 2022;377(6613):1399-1406. PubMed PMID: 36137043.

    Comment in “A coagulation factor moonlights in the heart”. Tong D, Hill JA. Science. 2022 Sep 23;377(6613):1382-1383. PubMed PMID: 36137028.

    1. Wang      YC, Koay YC, Pan C, Zhou Z, Wilson Tang WH, Wilcox J, Li XS, Zagouras A,      Marques F, Allayee H, Rey FE, Kaye DM, O'Sullivan JF, Hazen SL, Cao      Y*, and Lusis AJ*. Indole-3-Propionic Acid Protects Against Heart Failure      With Preserved Ejection Fraction. Circulation Research. 2024 Feb 16;134(4):371-389. PubMed PMID: 38264909. (Featured article, Best Manuscript Award)

    Comment in “From Gut to Heart: Role of Indole-3-Propionic Acid in HFpEF”. Vacca A, Schiattarella GG. Circ Res. 2024 Feb 16;134(4):390-392. PubMed PMID: 38359099.

    1. Zhou J#, Zhang L#, Peng J#, Zhang X#, Zhang F#, Wu Y, Huang A,      Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang      D, Guo K, Feng Y, Yin S, Cao Y*,      Li T*, Jiang Y*.      Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates      brain ischemic stroke by suppressing ARF1 lactylation. Cell Metab.      2024 Jun 14:S1550-4131(24)00192-X. PMID: 38906140.

    2. He Q#, Ji L#, Wang Y#, Zhang Y#, Wang H, Wang J,      Zhu Q, Xie M, Ou W, Liu J, Tang K, Lu K, Liu Q, Zhou J, Zhao R, Cai X, Li      N, Cao Y*, Li T*. Acetate enables metabolic fitness      and cognitive performance during sleep disruption. Cell Metab.      2024 Sep 3;36(9):1998-2014.e15. doi: 10.1016/j.cmet.2024.07.019. Epub 2024      Aug 19. PMID: 39163862.

    3. Zuo X#, Zhao R#, Wu M#,      Wang Y#, Wang S#, Tang K, Wang Y, Chen J, Yan X*, Cao      Y*, Li T*. Multi-omic profiling of sarcopenia identifies disrupted      branched-chain amino acid catabolism as a causal mechanism and therapeutic      target. Nature Aging. 2025

    4. Cao Y, Pan      C, Wang Y-C, Zhou Z, Jedian V, Meng Y, Campbell G, Guardino K, Li C, Wang      J, and Lusis AJ. Identification of DNA Damage Repair Enzyme Ascc2 as      Causal for Heart Failure with Preserved Ejection Fraction (HFpEF). Circulation.      2022 Apr 5;145(14):1102-1104. PubMed PMID: 35377742.

    5. Cao Y, Vergnes L, Wang Y-C, Pan C, Krishnan      KC, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD,      Seldin MM, Wang J, Vondriska TM, Wang Y, Reue K, and Lusis AJ. Sex Differences      in Heart Mitochondria Regulate Diastolic Dysfunction. Nature      Communications. 13, 3850 (2022). PubMed      PMID: 35787630.

    6. Shen S, Tian B, Zhang H, Wang YC, Li T*, Cao Y*.      Heart Failure and Gut Microbiota: What Is Cause and Effect? Research      (Wash D C). 2025 Feb 20;8:0610. doi: 10.34133/research.0610. PubMed PMID:      39981296.

    9.     Cao Y#, Bojjireddy N#, Kim M, Li T, Zhai P, Nagarajan N, Sadoshima J, Palmiter RD, Tian R. Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury. Circulation Research. 2017 Oct 27;121(10):1182-1191. PubMed PMID: 28835357.

    10.  Cao Y#, Guo WT#, Tian S, He X, Wang XW, Liu X, Gu KL, Ma X, Huang D, Hu L, Cai Y, Zhang H, Wang Y*, Gao P*. miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency. EMBO J. 2015 Mar 4;34(5):609-23. PubMed PMID: 25603933.

    11.  Cao Y#, Aquino-Martinez R#, Hutchison E#, Allayee H, Lusis AJ*, and Rey FE. Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach. Mol Metab. 2022 Jul 20:101557. PubMed PMID: 35870705.

    12. Cao Y*, Lusis AJ, Coagulation factor with potential for the treatment of heart failure. Clin Transl Med. 2022; 00: e1144.

    13. Wang YC, Cao Y, Pan C., Zhou Z, Lusis AJ. Heterogeneity of small intestinal immune and epithelial cells and their cellular response network to a western diet. Journal of Experimental Medicine. 2023 220 (5): e20221437.

    14. Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, Strumwasser A, Cao Y, Clifford B, Ma A, Scumpia P, Shirihai O, Vallim T, Laakso M, Lusis AJ, Hevener A, Zhenqi Zhou. Parkin Regulates Adiposity by Coordinating Mitophagy with Mitochondrial Biogenesis in White Adipocytes. Nature Communications. 2022;13(1):6661. Published 2022 Nov 4. PubMed PMID: 36333379.