曹洋
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Cao Y, Wang Y-C, Zhou Z, Pan C, Jiang L, Zhou Z, Meng Y, Charugundla S, Li T, Allayee H, Seldin MM, and Lusis AJ. Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure. Science. 2022;377(6613):1399-1406. PubMed PMID: 36137043.
Comment in “A coagulation factor moonlights in the heart”. Tong D, Hill JA. Science. 2022 Sep 23;377(6613):1382-1383. PubMed PMID: 36137028.
Wang YC, Koay YC, Pan C, Zhou Z, Wilson Tang WH, Wilcox J, Li XS, Zagouras A, Marques F, Allayee H, Rey FE, Kaye DM, O'Sullivan JF, Hazen SL, Cao Y*, and Lusis AJ*. Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction. Circulation Research.
2024 Feb 16;134(4):371-389. PubMed PMID: 38264909. (Featured article, Best Manuscript Award)
Comment in “From Gut to Heart: Role of Indole-3-Propionic Acid in HFpEF”. Vacca A, Schiattarella GG. Circ Res. 2024 Feb 16;134(4):390-392. PubMed PMID: 38359099.
Zhou J#, Zhang L#, Peng J#, Zhang X#, Zhang F#, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y*, Li T*, Jiang Y*. Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation. Cell Metab. 2024 Jun 14:S1550-4131(24)00192-X. PMID: 38906140.
He Q#, Ji L#, Wang Y#, Zhang Y#, Wang H, Wang J, Zhu Q, Xie M, Ou W, Liu J, Tang K, Lu K, Liu Q, Zhou J, Zhao R, Cai X, Li N, Cao Y*, Li T*. Acetate enables metabolic fitness and cognitive performance during sleep disruption. Cell Metab. 2024 Sep 3;36(9):1998-2014.e15. doi: 10.1016/j.cmet.2024.07.019. Epub 2024 Aug 19. PMID: 39163862.
Zuo X#, Zhao R#, Wu M#, Wang Y#, Wang S#, Tang K, Wang Y, Chen J, Yan X*, Cao Y*, Li T*. Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target. Nature Aging. 2025
Cao Y, Pan C, Wang Y-C, Zhou Z, Jedian V, Meng Y, Campbell G, Guardino K, Li C, Wang J, and Lusis AJ. Identification of DNA Damage Repair Enzyme Ascc2 as Causal for Heart Failure with Preserved Ejection Fraction (HFpEF). Circulation. 2022 Apr 5;145(14):1102-1104. PubMed PMID: 35377742.
Cao Y, Vergnes L, Wang Y-C, Pan C, Krishnan KC, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD, Seldin MM, Wang J, Vondriska TM, Wang Y, Reue K, and Lusis AJ. Sex Differences in Heart Mitochondria Regulate Diastolic Dysfunction. Nature Communications. 13, 3850 (2022). PubMed PMID: 35787630.
Shen S, Tian B, Zhang H, Wang YC, Li T*, Cao Y*. Heart Failure and Gut Microbiota: What Is Cause and Effect? Research (Wash D C). 2025 Feb 20;8:0610. doi: 10.34133/research.0610. PubMed PMID: 39981296.
9. Cao Y#, Bojjireddy N#, Kim M, Li T, Zhai P, Nagarajan N, Sadoshima J, Palmiter RD, Tian R. Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury. Circulation Research. 2017 Oct 27;121(10):1182-1191. PubMed PMID: 28835357.
10. Cao Y#, Guo WT#, Tian S, He X, Wang XW, Liu X, Gu KL, Ma X, Huang D, Hu L, Cai Y, Zhang H, Wang Y*, Gao P*. miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency. EMBO J. 2015 Mar 4;34(5):609-23. PubMed PMID: 25603933.
11. Cao Y#, Aquino-Martinez R#, Hutchison E#, Allayee H, Lusis AJ*, and Rey FE. Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach. Mol Metab. 2022 Jul 20:101557. PubMed PMID: 35870705.
12. Cao Y*, Lusis AJ, Coagulation factor with potential for the treatment of heart failure. Clin Transl Med. 2022; 00: e1144.
13. Wang YC, Cao Y, Pan C., Zhou Z, Lusis AJ. Heterogeneity of small intestinal immune and epithelial cells and their cellular response network to a western diet. Journal of Experimental Medicine. 2023 220 (5): e20221437.
14. Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, Strumwasser A, Cao Y, Clifford B, Ma A, Scumpia P, Shirihai O, Vallim T, Laakso M, Lusis AJ, Hevener A, Zhenqi Zhou. Parkin Regulates Adiposity by Coordinating Mitophagy with Mitochondrial Biogenesis in White Adipocytes. Nature Communications. 2022;13(1):6661. Published 2022 Nov 4. PubMed PMID: 36333379.