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科学研究
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Publications (Selected from 36)   * Co-first author, # Corresponding author

1.     Sun SY, Nie LY, Fang X, Luo HM, Fu C, Wei Z, Tang AH (2025) The KIF21A-KANK1 interaction regulates dendritic morphology and synapse plasticity in neurons. Neural Regen Res. 20(1):209-223.

2.     Chen JH#, Tang AH# (2023) Nanoscale reorganization of glutamate receptors underlies synaptic plasticity and pathology. Neurosci Bull. In press.

3.     Xu N*, Cao R*, Chen SY, Gou XZ, Wang B, Luo HM, Gao F, Tang AH (2024) Structural and functional reorganization of inhibitory synapses by activity-dependent cleavage of neuroligin-2. Proc. Natl. Acad. Sci. U.S.A., 121(18): e2314541121.

4.     Chen JH*#, Xu N*, Qi L, Yan HH, Wan FY, Gao, F, Fu C, Cang C, Lu B, Bi GQ, Tang AH# (2023) Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington’s disease. Cell Reports, 42(12): 113573.

5.     He J, Liu K, Wu Y, Zhao C, Yan S, Chen JH, Hu L, Wang D, Zheng F, Wei W, Xu C, Huang C, Liu X, Yao X,  Ding L, Fang Z#, Tang AH#, Fu C# (2023) The AAA-ATPase Yta4/ATAD1 interacts with Dnm1 and Fis1 to inhibit mitochondrial fission.  Plos Bio., 21(8): e3002247.

6.     Li D, Cao R, Li Q, Yang Y, Tang AH, Zhang J, Liu Q (2023) Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment. Nat Struct Mol Biol, 30(7):914-925.

7.     Zhu WH, Yang XX, Gou XZ, Fu SM, Chen JH, Gao F, Shen Y, Bi D#, Tang, AH# (2023) Nanoscale reorganization of synaptic proteins in Alzheimer’s disease. Neuropathol. Appl. Neurobiol. 49(4):e12924.

8.     Li J*, Shang Z*, Chen JH* , Gu W*, Yao L*, Yang X, Sun X, Wang L, Wang T, Liu S, Li J, Hou T, Xing D, Gill DL, Li J, Wang SQ, Hou L, Zhou Y#, Tang AH#, Zhang X#, Wang Y# (2023) Engineering of NEMO as calcium indicators with large dynamics and high sensitivity. Nat Methods, 20: 918–924.

9.     Han Y*, Cao R*, Qin L, Chen LY, Tang AH#, Südhof TC#, Zhang B# (2022) Neuroligin3 confines AMPA receptors in nanoclusters and controls synaptic strength at the calyx of Held. Sci Adv., 8(24): eabo4173.

10.  Sarkar D, Kang J, Wassie AT, Schroeder ME, Peng Z, Tarr TB, Tang AH, Niederst ED, Young JZ, Su H, Park D, Yin P, Tsai LH, Blanpied TA, Boyden ES (2022) Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy. Nat Biomed Eng, 6(9):1057-1073.

11.  Sun SY, Cao R, Zh Y, Sheng N#, Tang AH# (2022) Correlative assembly of subsynaptic nanoscale organizations during development. Front Synaptic Neurosci, 14:748184.

12.Gou XZ*, Ramsey AM*#, Tang AH# (2022) Re-examination of the determinants of synaptic strength from the perspective of superresolution imaging. Curr Opin Neurobiol, 74:102540.

13.Ramsey A*, Tang AH*, LeGates TA, Gou XZ, Carbone BE, Thompson SM,  Biederer T and Blanpied TA (2021) Subsynaptic positioning of AMPARs by LRRTM2 controls synaptic strength. Sci Adv. 7(34): eabf3126.

14. Chen JH, Blanpied TA and Tang AH# (2020) Quantification of Trans-synaptic Protein Alignment: A Data Analysis Case for Single-molecule Localization Microscopy. Methods. 174: 72-80.

15.  Chen H*, Tang AH*, and Blanpied TA# (2018) Subsynaptic spatial organization as a regulator of synaptic strength and plasticity. Curr. Opin. Neurobiol.51:147-153.

16.  Mengistu M, Tang AH, Foulke, JS Jr., Blanpied TA, Gonzalez M, Spouge J, Lewis GK and DeVico AL# (2017) Patterns of Conserved gp120 Epitope Presentation on Attached HIV-1 Virions. Proc. Natl. Acad. Sci. U.S.A. 114(46):E9893-E9902.

17.  Tang AH*#, Chen H*, Li TP, Metzbower SR, Mac Gillavry HD and Blanpied TA# (2016) A transsynaptic nanocolumn aligns neurotransmitter release to receptors. Nature. 536: 210–214.

18.  Tang AH# and Alger BE (2015) Homer protein–metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of Fragile X Syndrome. J Neurosci. 35(9):3938-45.

19. Tang AH, Karson MA, Nagode DA, McIntosh JM, Uebele VN, Renger JJ, Klugmann M, Milner TA, Alger BE# (2011) Nerve terminal nAChRs initiate quantal GABA release from perisomatic interneurons by activating axonal T-type (Cav3) Ca2+ channels and Ca2+ release from stores. J Neurosci, 31: 13546 - 13561.

20.  Tang AH#, Wang SQ (2009) Transition of spiral calcium waves between multiple stable patterns can be triggered by a single calcium spark in a fire-diffuse-fire model. Chaos, 19: 037114-037114-6.