Selected Publications

 

Yao X, Cheng L & Forte JG. (1996). Characterization of the interaction of gastric ezrin with actin. J Biol Chem. 271, 7224-7229.

 

Yao X, Anderson KL, & Cleveland DW. (1997). The microtubule-dependent motor CENP-E is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. J Cell Biol. 139, 435-447.

 

Yao X, Zheng Y, Sullivan KF, & Cleveland DW. (2000). CENP-E forms a link between attachment of spindle microtubules to kinetochore and the mitotic checkpoint. Nat Cell Biol. 2, 484-491.

 

Wang H, Hu X, Ding X, Dou Z, Yang Z, Shaw AW. Teng M, Cleveland DW, Goldberg ML, Niu L, & Yao X. (2004). Human Zwint-1 specifies localization of ZW10 to kinetochores and is essential for mitotic checkpoint signaling. J Biol Chem. 279, 54590-8.

 

Xue Y, Zhou F, Lu H, Chen G, & Yao X. (2005). GPS: a comprehensive www server for phosphorylation sites prediction. Nucleic Acids Res. 33, W184-7.

 

Fang Z, Miao Y, Ding X, Deng H, Liu S, Wang F, Zhou R, Watson C, Fu C, Hu Q, Lillard JW Jr, Powell M, Chen Y, Forte JG, & Yao X. (2006). Proteomic identification and functional characterization of a novel ARF6 GTPase-activating protein ACAP4. Mol Cell Proteomics. 5, 1437-1449. (Cover story)

 

Fu G, Ding X, Yuan K, Aikhionbare F, Yao J, Cai X, Jiang K, & Yao X. (2007). Phosphorylation of Sgo1 by NEK2A is essential for chromosome segregation. Cell Res. 17, 608-618. (Cover story)

 

Xue Y, Ren J, Gao X, Jin C, Wen L, & Yao X. (2008). GPS 2.0: Prediction of kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics. 7, 1598-608.

 

Jiang K, Wang J, Liu J, Ward T, Wordeman L, Davidson A, Wang F, & Yao X. (2009). TIP150 interacts with and targets MCAK to the plus-end of microtubules. EMBO Rep. 10, 857-65.

 

Ding X, Yan F, Yao P, Yang Z, Wan W, Wang X, Liu J, Gao X, Abrieu A, Zhu T, Zhang J, Dou Z, & Yao X. (2010). Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin. Cell Res. 20, 1386-9.

 

Chen J, Yao Y, Gong C, Yu F, Su S, Chen J, Liu B, Deng H, Yao H, Su F, Anderson KS, Liu Q, McEwen M, Yao X, & Song E. (2011). CCL18 from tumor associated macrophages promotes breast cancer metastasis via CCR18. Cancer Cell. 19, 541-55. (Highlighted by Cancer cell)

 

Xia P, Wang Z, Liu X, Zhang L, Dou Z, Ding X, & Yao X. (2012). Acetylation-dependent regulation of kinetochore microtubule signaling by PCAF acetyltransferase. Proc Natl Acad Sci U S A. 109, 16564-9. (Recommended by F1000)

 

Zhao X, Wang D, Liu X, Liu L, Song Z, Zhu T, Adams G, Gao X, Tian R, Huang Y, Chen R, Wang F, Liu D, Yu X, Chen Y, Chen Z, Teng M, Ding X, & Yao X. (2013). Phosphorylation of BAR domain of ACAP4 regulates membrane tubulation. Proc Natl Acad Sci U S A. 110, 11023-8.

 

Dou Z, Liu X, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL, & Yao X. (2015). Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment. Proc Natl Acad Sci U S A. 112, 4546-4556.

 

Mo F, Zhuang X, Liu X, Yao PY, Qin B, Su Z, Zang J, Wang Z, Zhang J, Dou Z, Tian C, Teng M, Niu L, Hill DL, Fang G, Ding X, Fu C, & Yao X. (2016). Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation. Nat Chem Biol.12, 226-32. (Highlighted by Nat Chem Biol)

 

Huang Y, Lin L, Liu X, Ye S, Yao PY, Wang W, Yang F, Gao X, Li J, Zhang J, YangZ, Liu X, Yang Z, Zang J, Teng M, Wang Z, Ruan K, Ding X, Li L, Cleveland DW, Zhang R, & Yao X. (2019). BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res. 29, 562-578. (Highlighted by Cell Research)

 

Xu L, Ali M, Duan W, Yuan X, Garba F, Mullen M, Sun B, Poser I, Duan H, Lu J, Tian R, Ge Y, Chu L, Pan W, Wang D, Hyman A, Green H, Li L, Dou Z, Liu D, Liu X, & Yao X. (2021). Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation. Cell Rep. 36, 109343.

 

Song X, Yang F, Liu X, Xia P, Yin W, Wang Z, Wang Y, Yuan X, Dou Z, Jiang K, Ma M, Hu B, Zhang R, Xu C, Zhang Z, Ruan K, Tian R, Li L, Liu T, Hill DL, Zang J, Liu X, Li J, Cheng J, & Yao X. (2021). Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis. Nat Chem Biol. 17, 1314-1323. (Highlighted by Nat Chem Biol)

 

Tian T, Chen L, Dou Z, Yang Z, Gao X, Yuan X, Wang C, Liu R, Shen Z, Gui P, Teng M, Meng X, Hill DL, Li L, Zhang X, Liu X, Sun L, Zang J, & Yao X. (2022). Structural insights into human CCAN complex assembled onto DNA. Cell Discov. 8, 90. 

 

Song X, Yang F, Yang T, Yin W, Wang Z, Wang Y, Yuan X, Dou Z, Jiang K, Ma M, Hu B, Zhang R, Xu C, Zhang Z, Ruan K, Tian R, Li L, Liu T, Hill DL, Zang J, Liu X, & Yao X. (2023). Phase separation of EB1 guides microtubule plus-end dynamics. Nat Cell Biol. 25, 79-91. (Highlighted by Nat Cell Biol)

 

Wen YH, Yang F, Li S, Yao X, Song J, & Gong LZ. (2023). Diastereodivergent desymmetric annulation to access spirooxindoles: chemical probes for mitosis. J Am Chem Soc. 145, 4199–4207.

 

Ren Q, Li L, Liu L, Li J, Shi C, Sun Y, Yao X, Hou Z, & Xiang S. (2025). The molecular mechanism of temperature-dependent phase separation of heat shock factor 1. Nat Chem Biol. 21, 831-842. 

 

Zhang L, Stauffer W,Liu C, Shao H, Abuzahriyeh N, Jiang R, Zwicker D,Liu X, Yao X, & Dernburg AF. (2025). Crossover patterning through condensation and coarsening of pro-crossover factors. Nat Cell Biol. 27, 1161-1174. (Cover story)

 

 

Review

 

Forte JG, & Yao X. (1996). The membrane-recruitment-and-recycling hypothesis of gastric HCl secretion. Trends in Cell Biology. 6, 45-48.

 

Yao X, & Forte JG. (2003). Cell biology of acid secretion in the stomach. Ann Rev Physiol. 65, 103-131.

 

Yao X, & Smolka A. (2019). Gastric parietal cell physiology and Helicobacter pylori-elicited diseases. Gastroenterology. 156, 2158–2173.

 

Liu X, Liu X, Wang H, Dou Z, Ruan K, Hill DL, Li L, Shi Y, & Yao X. (2020). Phase separation drives decision making in cell division. J Biol Chem. 295, 13419-13431. (Cover story)

 

 

Comment

 

Yu H, & Yao X. (2008). Cyclin B1: conductor of mitotic symphony orchestra. Cell Res. 18, 218-20.

 

Yao X, & Fang G. 2009. Visualization and orchestration of dynamic molecular society in cells. Cell Res. 19, 152-155.

 

Yao X, Li D, & Pei G. (2013) In focus: Molecular and Cell Biology Research in China. Nat Rev Mol Cell Biol. 14, 600-606.