Paper Publications

[1] Qi, Y.-K..Mirror-image protein and peptide drug discovery through mirror-image phage display.Chem.2024,10,:2309-2407
[2] Dong-Liang Huang; Wu-Chen Guo; Wei-Wei Shi; Yun-Pu Gao; Yong-Kang Zhou; Long-Jie Wang; Chen Wang; Tang, S.*; Liu, L.*; Zheng, J. S.*.Enhanced Native Chemical Ligation by Peptide Conjugation in Trifluoroacetic Acid.Sci. Adv..2024,10,:eado9413
[3] Gao, Y.-P.; Sun, P.-F.; Guo, W.-C.; Zhou, Y.-K.; Zheng, J. S.*; Tang, S.*.Chemical synthesis of a 28 kDa full-length PET degrading enzyme ICCG by the removable backbone modification strategy.Bioorg. Chem..2024,143,:10747
[4] Li, Y.; Wang, L.-J.; Zhou, Y.-K.; Liang, J.; Xiao, B.; Zheng, J. S.*.An improved installation of 2-hydroxy-4-methoxybenzyl (iHmb) method for chemical protein synthesis.Chin. Chem. Lett..2024,35,:109033
[5] Zheng, Y.; Zhang, B.; Shi, W. W.; Deng, X.; Wang, T. Y.; Han, D.; Ren, Y.; Yang, Z.; Zhou, Y. K.; Kuang, J.; Wang, Z.W.; Tang, S.; Zheng, J. S.*.An Enzyme-Cleavable Solubilizing-Tag Facilitates the Chemical Synthesis of Mirror-Image Proteins.Angew. Chem. Int. Ed..2024,63,:e202318897
[6] Shi, W. W.; Wang, T. Y.; Yang, Z. Y.; Ren, Y. X.; Han, D. Y.; Zheng, Y. P.; Deng, X. Y.; Tang, S.; Zheng, J. S.*.L-Glycosidase-Cleavable Natural Glycans Facilitate the Chemical Synthesis of Correctly Folded Disulfide-Bonded D-Proteins.Angew. Chem. Int. Ed..2024,63,:e202313640
[7] Zhang, B.; Zheng, Y.; Chu, G.; Deng, X.; Wang, T.; Shi, W.; Zhou, Y.; Tang, S.; Zheng, J. S.*; Liu, L.*.Backbone‐Installed Split Intein‐Assisted Ligation for the Chemical Synthesis of Mirror‐Image Proteins.Angew. Chem. Int. Ed..2023,62,:e202306270
[8] Ding, R. C.; Shi, W. W.; Zheng, J. S.*.Chemically Synthetic D-Sortase Enables Enzymatic Ligation of D-Peptides.Org. Lett..2023,25,:4857-4861
[9] Han, D. Y.; Ren, Y. X.; Yang, Z. Y.; Huang, H.; Zheng, J. S.*.Split Intein: a Versatile Tool for Traceless Peptide Segment Ligation.Chem. J. Chinese U..2023,44,:20230188
[10] Shi, W. W.; Shi, C.; Wang, T. Y.; Li, Y. L.; Zhou, Y. K.; Zhang, X. H.; Bierer, D.; Zheng, J. S.*; Liu, L.*.Total Chemical Synthesis of Correctly Folded Disulfide-Rich Proteins Using a Removable O-Linked beta-N-Acetylglucosamine Strategy.J. Am. Chem. Soc..2022,144,:349-357
[11] Li, Y.; Heng, J.; Sun, D.; Zhang, B.; Zhang, X.; Zheng, Y.; Shi, W. W.; Wang, T. Y.; Li, J. Y.; Sun, X.; Liu, X.; Zheng, J. S.*; Kobilka, B. K.; Liu, L.*.Chemical Synthesis of a Full-Length G-Protein-Coupled Receptor beta2-Adrenergic Receptor with Defined Modification Patterns at the C-Terminus.J. Am. Chem. Soc..2021,143,:17566-17576
[12] Montigny, C.; Huang, D. L.; Beswick, V.; Barbot, T.; Jaxel, C.; le Maire, M.; Zheng, J. S.*; Jamin, N..Sarcolipin alters SERCA1a interdomain communication by impairing binding of both calcium and ATP.Sci. Rep..2021,11,:1641
[13] Li, Y.; Cao, X.; Tian, C.; Zheng, J. S.*.Chemical protein synthesis-assisted high-throughput screening strategies for d-peptides in drug discovery.Chin. Chem. Lett..2020,31,:2365-2374
[14] Huang, D.-L.; Li, Y.; Liang, J.; Yu, L.; Xue, M.; Cao, X.-X.; Xiao, B.; Tian, C.-L.; Liu, L.; Zheng, J. S.*.The New Salcylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis.J. Am. Chem. Soc..2020,142,:8790-8799
[15] Qu, Q.; Gao, S.; Wu, F. M.; Zhang, M. G.; Li, Y; Zhang, L. H., Donald Bierer, Tian, C. L.*, Zheng, J. S.*; Liu, L.*.Synthesis of disulfide surrogate peptides incorporating large-span surrogate bridges through a native chemical ligation-assisted diaminodiacid strategy.Angew. Chem. Int. Ed..2020,59,:6037-6045

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