Scientific Research
Research Field
Paper Publications
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Qi, Y.-K.,Zheng, J. S.*,Liu, L.*.Mirror-image protein and peptide drug discovery through mirror-image phage display.Chem,2024,10,2309-2407.
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Dong-Liang Huang; Wu-Chen Guo; Wei-Wei Shi; Yun-Pu Gao; Yong-Kang Zhou; Long-Jie Wang; Chen Wang; Tang, S.*; Liu, L.*; Zheng, J. S.*,Enhanced Native Chemical Ligation by Peptide Conjugation in Trifluoroacetic Acid.Sci. Adv.,2024,10,eado9413.
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Gao, Y.-P.; Sun, P.-F.; Guo, W.-C.; Zhou, Y.-K.; Zheng, J. S.*; Tang, S.*,Chemical synthesis of a 28 kDa full-length PET degrading enzyme ICCG by the removable backbone modification strategy.Bioorg. Chem.,2024,143,10747.
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Li, Y.; Wang, L.-J.; Zhou, Y.-K.; Liang, J.; Xiao, B.; Zheng, J. S.*,An improved installation of 2-hydroxy-4-methoxybenzyl (iHmb) method for chemical protein synthesis.Chin. Chem. Lett.,2024,35,109033.
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Zheng, Y.; Zhang, B.; Shi, W. W.; Deng, X.; Wang, T. Y.; Han, D.; Ren, Y.; Yang, Z.; Zhou, Y. K.; Kuang, J.; Wang, Z.W.; Tang, S.; Zheng, J. S.*,An Enzyme-Cleavable Solubilizing-Tag Facilitates the Chemical Synthesis of Mirror-Image Proteins.Angew. Chem. Int. Ed.,2024,63,e202318897.
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Shi, W. W.; Wang, T. Y.; Yang, Z. Y.; Ren, Y. X.; Han, D. Y.; Zheng, Y. P.; Deng, X. Y.; Tang, S.; Zheng, J. S.*,L-Glycosidase-Cleavable Natural Glycans Facilitate the Chemical Synthesis of Correctly Folded Disulfide-Bonded D-Proteins.Angew. Chem. Int. Ed.,2024,63,e202313640.
Patents
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郑基深; 孙鹏飞; 周永康 ,Invent,一种塑料降解酶及其镜像对映体、化学合成方法,2023-05-18,
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刘磊;郑基深;石威巍 ,Invent,制备活性铁调节激素的方法,202111108846.3,2021-09-22,CN 113817043 B,2023-07-25.
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郑基深;薛敏;李影;周永康; ,Invent,可脱除骨架修饰快速脱除的新方法及应用,202110516503.4,2021-05-12,CN 113264979B,2023-06-16.
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刘磊;郑基深;胡宏岗;田长麟;梁军;石威巍;李影 ,Invent,镜像蛋白信息存储与编码技术,2020-11-25,CN 112489721 B,2021-11-12.
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刘磊;郑基深;左超;唐姗;田长麟 ,化合物及其制备方法和应用,2016-02-16,CN 105622424 B,2018-08-03.
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郑基深;唐姗;司岩岩;刘磊;田长麟 ,一种化合物及其制备方法及利用其制备多肽的方法,2015-01-25,CN 104744327 B,2016-08-24.
Published Books
Research Projects
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郑基深
ZipCode:4033d038a97fa8a1e181832fb7374e02602ee696c0157a059ba3dede124bef920ced6426ac54dc14fe958f2764201685f155445b71f34a1bdb26d49a8e19909d5f12885d72e4a9af17189d12b56d9797e98a5aea30fc139d96a35fa624a75258ef4cb0d7f98f359ba300538a65269993f6dbe7be389418af3015b379354515cd
PostalAddress:0bfbcd599dc24684ca86444a3e3266712e820ea300dae3b443d952961ace072d1702c37b2586e21c991d8eeecb995bc1a83c925f9d10e38ba5bd8db39f390cbeaa0bde92c3abe47ae12a268b432bfa60b19290eaeacaeea30772fabae4c08170ae87987dcb93587ac63c74bb6aad17b1b6fee32fbbb6737e3c4a4c079cce8d91
OfficePhone:bbac8e795dd2678e5aa36e2006fda0d066e0b96727a9207d4a3ac13e97937777b08d40bce3bccddc2ec61f6be64efdfde367be01e358eb3d6a31eaab0fe4a382f08e820bd3c93762fbac574e9628c1ec53484332bef96c0119e035a9f4b3eb918ea487a546f8928b64db6591b8924abef3964c04bb2433b6de2014d14e485d13
Telephone:992ec3b527c10e149dd4b54bbaaebc0c0d3b0d16e2a2faef0bcb57883a674724f2db62430a8a6b1a0b7728e99599a487e94d7e098e7d5e0b8c2b67131565f993721a24dcb5f4d65905f723362524d9c803698e2106f855c68c7d55f5b4c123bde39da13b5eb9168826783ead01b5cf57b0e249df8bb9dbca25dc17f553cf90ee
Email:8c8f36b87a976462da230fc9fcaf507b1760c19ce29e877198cffb8e26c9eef2b1e6714d34f5dab1971c9951464e56f534dad7f7b20038c5ccff304d13edcaaaa0fd512c0a36def8fc2179ae7314f982cce8798da438fb93808f6c7325ad707f0692706d13eb8c0fa7ce2c90d9348e0704f8a5b672639d6130265e4bf49a2e2f
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